Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.48 |
| ▸ | RHEB | Q15382 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362023 | 0.89 | RHEB (0.57) | DGAT1RHEBPTGESTP53 | |
| SCHEMBL2361142 | 0.86 | DGAT1 (0.44) | DGAT1RHEBPTGESMAPTNR2E3 | |
| SCHEMBL2361214 | 0.85 | CSNK1E (0.52) | DGAT1RHEBMAPTTP53 | |
| SCHEMBL2365435 | 0.84 | PTGES (0.48) | DGAT1PTGESMAPTNR2E3TP53 | |
| SCHEMBL2361026 | 0.83 | DGAT1 (0.41) | DGAT1RHEBPTGESMAPTNR2E3 | |
| SCHEMBL2361492 | 0.80 | NR2E3 (0.64) | DGAT1MAPTNR2E3TP53 | |
| SCHEMBL2361432 | 0.79 | KDM4E (0.47) | DGAT1RHEBPTGESMAPTTP53 | |
| SCHEMBL2362063 | 0.78 | KDM4E (0.47) | DGAT1RHEBPTGESMAPTTP53 | |
| SCHEMBL2361818 | 0.77 | RAB9A (0.47) | RHEBPTGESMAPTTP53 | |
| SCHEMBL2362094 | 0.77 | PTGER4 (0.44) | DGAT1PTGESMAPTNR2E3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |