Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.57 |
| ▸ | PTGES | O14684 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361214 | 0.91 | CSNK1E (0.52) | RHEBKDM4EALDH1A1NPC1PKM | |
| SCHEMBL2361289 | 0.89 | DGAT1 (0.48) | RHEBPTGESDGAT1TP53 | |
| SCHEMBL2360771 | 0.86 | PTGES (0.50) | PTGESKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL2361432 | 0.85 | KDM4E (0.47) | RHEBPTGESKDM4EALDH1A1LMNA | |
| SCHEMBL2362063 | 0.84 | KDM4E (0.47) | RHEBPTGESKDM4EALDH1A1LMNA | |
| SCHEMBL2361142 | 0.84 | DGAT1 (0.44) | RHEBPTGESLMNANPC1RAB9A | |
| SCHEMBL2361818 | 0.83 | RAB9A (0.47) | RHEBPTGESKDM4EALDH1A1LMNA | |
| SCHEMBL1251886 | 0.82 | DGAT1 (0.65) | RHEBKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL2361754 | 0.82 | PRSS12 (0.56) | PTGESKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL2361026 | 0.81 | DGAT1 (0.41) | RHEBPTGESALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |