SCHEMBL236257

SCHEMBL236257

N[C@@H](CCC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.64
GRM8 O00222 1/20 0.64
GRM6 O15303 1/20 0.64
GRIN2D O15399 1/20 0.64
GRIN3B O60391 1/20 0.64
GSR P00390 1/20 0.64
CYP1A2 P05177 1/20 0.64
GRIK1 P39086 1/20 0.64
GRM5 P41594 1/20 0.64
GRIA1 P42261 1/20 0.64
GRIA2 P42262 1/20 0.64
GRIA3 P42263 1/20 0.64
SLC1A3 P43003 1/20 0.64
SLC1A2 P43004 1/20 0.64
SLC1A1 P43005 1/20 0.64
GRIA4 P48058 1/20 0.64
GRIN1 Q05586 1/20 0.64
GRIN2A Q12879 1/20 0.64
GRIK2 Q13002 1/20 0.64
GRIK3 Q13003 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30973852 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL30973850 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL1769459 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL12210209 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL9223132 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL9225173 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL6853383 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL9688034 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL22750154 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL30973851 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015393-A1 NOVEL NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INT (DE) 2026-01-15 US claimed
US-20250382344-A1 Soluble GLP1/GIP/NPY2 Receptor Triple Agonists BOEHRINGER INGELHEIM INT GMH (DE) 2025-12-18 US claimed
US-20250326814-A1 MODIFIED OXYNTOMODULIN AND METHODS OF USE THEREOF OPKO BIOLOGICS LTD. (IL) 2025-10-23 US claimed
CN-118451091-A Cleavable radioligands for targeting cell surface receptors and uses thereof 辐联科技香港有限公司 2024-08-06 CN claimed
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 US claimed
CN-117677302-A Peptide compounds for flavor modulation CJ第一制糖株式会社 2024-03-08 CN claimed
US-20230410977-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES 2023-12-21 US claimed
US-20230103631-A1 PEPTIDES AS SELECTIVE GIP RECEPTOR AGONISTS SANOFI (FR) 2023-04-06 US claimed
CN-115884982-A Peptides as selective GIP receptor agonists 赛诺菲 2023-03-31 CN claimed
EP-4110800-A1 PEPTIDES AS SELECTIVE GIP RECEPTOR AGONISTS SANOFI (FR) 2023-01-04 EP claimed
EP-1002535-A1 New use of glutamate antagonists for the treatment of cancer Ikonomidou, Hrissanthi (DE) 2000-05-24 EP claimed
WO-2000024395-A1 NEW USE OF GLUTAMATE ANTAGONISTS FOR THE TREATMENT OF CANCER IKONOMIDOU HRISSANTHI (DE) 2000-05-04 WO claimed
EP-0559175-B1 gamma-Polyglutamate hydrolase and process for producing same MEIJI SEIKA KAISHA (JP) 1999-07-14 EP claimed
US-5757408-A PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING XEROX CORPORATION (US) 1998-05-26 US claimed
US-5683793-A Ink jet transparencies XEROX CORPORATION (US) 1997-11-04 US claimed
US-5444061-A Antitumor agents BRITISH TECHNOLOGY GROUP LIMITED (GB) 1995-08-22 US claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
US-5356805-A Gamma-polyglutamate hydrolase MEIJI SEIKA KAISHA, LTD. (JP) 1994-10-18 US claimed
EP-0559175-A2 gamma-Polyglutamate hydrolase and process for producing same MEIJI SEIKA KAISHA LTD. (JP) 1993-09-08 EP claimed
EP-0266905-A1 Reagents for assay of gamma-glutamyl-transpeptidase UNITIKA LTD. (JP) 1988-05-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015393-A1 NOVEL NMU RECEPTOR 2 AGONISTS NMUR2, NMUR1, GPR18 FOLH1 547/4885GRM8 151/4885GRM6 248/4885
US-20250326814-A1 MODIFIED OXYNTOMODULIN AND METHODS OF USE THEREOF OGFRL1, OXGR1, THOP1 FOLH1 1679/4885GRM8 690/4885GRM6 430/4885
US-20250382344-A1 Soluble GLP1/GIP/NPY2 Receptor Triple Agonists GLP1R, GIPR, NPY1R FOLH1 479/4885GRM8 962/4885GRM6 1031/4885
US-20230103631-A1 PEPTIDES AS SELECTIVE GIP RECEPTOR AGONISTS GIPR, GLP1R, GPR119 FOLH1 740/4885GRM8 275/4885GRM6 365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.