SCHEMBL9688034

SCHEMBL9688034

N[C@@H](CCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.64
GRM8 O00222 1/20 0.64
GRM6 O15303 1/20 0.64
GRIN2D O15399 1/20 0.64
GRIN3B O60391 1/20 0.64
GSR P00390 1/20 0.64
CYP1A2 P05177 1/20 0.64
GRIK1 P39086 1/20 0.64
GRM5 P41594 1/20 0.64
GRIA1 P42261 1/20 0.64
GRIA2 P42262 1/20 0.64
GRIA3 P42263 1/20 0.64
SLC1A3 P43003 1/20 0.64
SLC1A2 P43004 1/20 0.64
SLC1A1 P43005 1/20 0.64
GRIA4 P48058 1/20 0.64
GRIN1 Q05586 1/20 0.64
GRIN2A Q12879 1/20 0.64
GRIK2 Q13002 1/20 0.64
GRIK3 Q13003 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30973852 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL30973850 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL1769459 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL12210209 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL9223132 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL9225173 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL236257 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL6853383 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL22750154 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL30973851 1.00 FOLH1 (0.64) FOLH1GRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015393-A1 NOVEL NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INT (DE) 2026-01-15 US claimed
US-20250382344-A1 Soluble GLP1/GIP/NPY2 Receptor Triple Agonists BOEHRINGER INGELHEIM INT GMH (DE) 2025-12-18 US claimed
US-20240382630-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES UK LIMITED (GB) 2024-11-21 US claimed
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP disclosed
US-20260015393-A1 NOVEL NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INT (DE) 2026-01-15 US disclosed
US-20250382344-A1 Soluble GLP1/GIP/NPY2 Receptor Triple Agonists BOEHRINGER INGELHEIM INT GMH (DE) 2025-12-18 US disclosed
EP-4648849-A1 NMU RECEPTOR 2 AGONISTS Boehringer Ingelheim International GmbH (DE) 2025-11-19 EP disclosed
US-12427187-B2 Glucose-responsive insulin conjugates MERCK SHARP & DOHME LLC (US) 2025-09-30 US disclosed
US-20250099632-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES UK LIMITED (GB) 2025-03-27 US disclosed
US-12214059-B2 Cleavable radioligands for targeting cell surface receptors and uses thereof FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2025-02-04 US disclosed
WO-2024245407-A1 CONJUGATES AND USES THEREOF FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2024-12-05 WO disclosed
WO-2024133382-A1 GLP1/GIP/NPY2 RECEPTOR TRIPLE AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-06-27 WO disclosed
WO-2023097038-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES U.S. INC. (US) 2023-06-01 WO disclosed
US-20220233647-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES MERCK SHARP & DOHME CORP. (US) 2022-07-28 US disclosed
EP-3980052-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES MERCK SHARP & DOHME CORP. (US) 2022-04-13 EP disclosed
WO-2020247297-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES MERCK SHARP & DOHME CORP. (US) 2020-12-10 WO disclosed
US-20190274334-A1 COMPOUNDS THAT MODULATE CALCIUM-SENSING RECEPTOR ACTIVITY FOR MODULATING KOKUMI TASTE AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2019-09-12 US disclosed
WO-2017181062-A1 COMPOUNDS THAT MODULATE CALCIUM-SENSING RECEPTOR ACTIVITY FOR MODULATING KOKUMI TASTE AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2017-10-19 WO disclosed
EP-0268377-B1 GLUTAMIC ACID DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM THE WELLCOME FOUNDATION LIMITED (GB) 1992-03-18 EP disclosed
EP-0268377-A2 Glutamic acid derivatives, processes and intermediates for their preparation and pharmaceutical formulations containing them THE WELLCOME FOUNDATION LIMITED (GB) 1988-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015393-A1 NOVEL NMU RECEPTOR 2 AGONISTS NMUR2, NMUR1, GPR18 FOLH1 547/4885GRM8 151/4885GRM6 248/4885
US-12427187-B2 Glucose-responsive insulin conjugates GPR119, IRS1, INSR FOLH1 410/4885GRM8 468/4885GRM6 189/4885
US-20240382630-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF ASGR1, GNRHR, SCTR FOLH1 22/4885GRM8 906/4885GRM6 1212/4885
US-20220233647-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES GPR119, IRS1, INSR FOLH1 410/4885GRM8 468/4885GRM6 189/4885
US-12214059-B2 Cleavable radioligands for targeting cell surface receptors and uses thereof ASGR1, GNRHR, SCTR FOLH1 22/4885GRM8 906/4885GRM6 1212/4885
US-20250099632-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF ASGR1, GNRHR, SCTR FOLH1 22/4885GRM8 906/4885GRM6 1212/4885
US-20250382344-A1 Soluble GLP1/GIP/NPY2 Receptor Triple Agonists GLP1R, GIPR, NPY1R FOLH1 479/4885GRM8 962/4885GRM6 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.