Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360920 | 0.80 | HCAR1 (0.50) | L3MBTL1CYP11B2OPRM1OPRD1OPRK1 | |
| SCHEMBL2362323 | 0.78 | CYP11B2 (0.50) | L3MBTL1CYP11B2OPRM1OPRD1OPRK1 | |
| SCHEMBL2853106 | 0.75 | ACSS2 (0.43) | MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL2362192 | 0.74 | CYP11B2 (0.46) | L3MBTL1CYP11B2MAPTALDH1A1KDM4E | |
| SCHEMBL26945304 | 0.72 | EGFR (0.52) | CYP11B2OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL17678354 | 0.71 | CYP11B2 (0.58) | L3MBTL1CYP11B2MAPTALDH1A1KDM4E | |
| SCHEMBL17586603 | 0.69 | EGFR (0.49) | CYP11B2OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL21148007 | 0.69 | EGFR (0.49) | CYP11B2OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL17586609 | 0.69 | EGFR (0.49) | CYP11B2OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL17586604 | 0.69 | EGFR (0.51) | CYP11B2OPRM1OPRD1OPRK1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |