Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 4/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 3/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362323 | 0.98 | CYP11B2 (0.50) | HCAR1MAPTKDM4EALDH1A1GFER | |
| SCHEMBL2362280 | 0.86 | CYP11B2 (0.47) | CYP11B2PRKACARPS6KB1GSK3BTLR8 | |
| SCHEMBL18960379 | 0.82 | TLR8 (0.45) | MAPTKDM4EALDH1A1CYP11B2PRKACA | |
| SCHEMBL14247637 | 0.81 | HCAR1 (0.48) | HCAR1MAPTKDM4EALDH1A1GFER | |
| SCHEMBL2362595 | 0.80 | L3MBTL1 (0.45) | HCAR1MAPTKDM4EALDH1A1GFER | |
| SCHEMBL21310845 | 0.79 | HCAR1 (0.50) | HCAR1MAPTKDM4EALDH1A1GFER | |
| SCHEMBL2362192 | 0.79 | CYP11B2 (0.46) | HCAR1MAPTKDM4EALDH1A1GFER | |
| SCHEMBL21311255 | 0.78 | OPRM1 (0.59) | HCAR1MAPTKDM4EALDH1A1GFER | |
| SCHEMBL17583061 | 0.78 | HCAR1 (0.45) | HCAR1MAPTKDM4EALDH1A1GFER | |
| SCHEMBL17582727 | 0.78 | CYP11B1 (0.49) | HCAR1MAPTKDM4EALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |