Sugi Predict

Sugi Predict / Compounds / SCHEMBL23626838

SCHEMBL23626838

SCHEMBL23626838

c1ccc2c(-c3nc(-c4cccc5ccccc45)nc(-c4cccc5c4oc4cc(-n6c7ccccc7c7cccnc76)ccc45)n3)cccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ HPGD P15428 2/20 0.37
▸ HSD17B10 Q99714 2/20 0.37
▸ GAA P10253 1/20 0.37
▸ NPC1 O15118 1/20 0.34
▸ TP53 P04637 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ TUBB4A P04350 1/20 0.33
▸ TUBB P07437 1/20 0.33
▸ TUBA3C P0DPH7 1/20 0.33
▸ TUBA1B P68363 1/20 0.33
▸ TUBA4A P68366 1/20 0.33
▸ TUBB4B P68371 1/20 0.33
▸ TUBB3 Q13509 1/20 0.33
▸ TUBB2A Q13885 1/20 0.33
▸ TUBB8 Q3ZCM7 1/20 0.33
▸ TUBA3E Q6PEY2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23626825 0.95 ALDH1A1 (0.34) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL23626813 0.93 KDM4E (0.33) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL23626889 0.91 TSHR (0.35) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL26082208 0.89 PRKDC (0.32) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL23626890 0.89 ALDH1A1 (0.34) ALDH1A1ALOX5PRKDCAKT1
SCHEMBL23626837 0.89 ALDH1A1 (0.34) ALDH1A1ALOX5PRKDCAKT1
SCHEMBL23626832 0.89 ALOX5 (0.35) KDM4EALDH1A1MAPTHSD17B10MAPK1
SCHEMBL23627207 0.89 KDM4E (0.39) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL23626888 0.88 ALDH1A1 (0.35) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL26082197 0.88 ALDH1A1 (0.34) KDM4EALDH1A1MAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873311-B2 Heterocyclic compound, organic electroluminescent device, and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2024-01-16 — — US disclosed
US-11873311-B2 Heterocyclic compound, organic electroluminescent device, and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2024-01-16 — — US disclosed
US-20230312604-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 — — US disclosed
US-20230312604-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 — — US disclosed
WO-2021136277-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312604-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC DEVICE ODC1, LEF1, PIEZO1 KDM4E 2765/4885ALDH1A1 137/4885MAPT 3152/4885
US-11873311-B2 Heterocyclic compound, organic electroluminescent device, and electronic device ODC1, LEF1, PIEZO1 KDM4E 2765/4885ALDH1A1 137/4885MAPT 3152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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