Ether

Ether

SCHEMBL23628495

CCOCC.Clc1ccc(Br)cc1.[MgH2]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.42
KDM4E B2RXH2 1/20 0.41
THRB P10828 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CCR5 P51681 5/20 0.38
KMT2A Q03164 2/20 0.38
P2RX7 Q99572 1/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 2/20 0.37
HTT P42858 1/20 0.37
MEN1 O00255 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
CYP2A6 P11509 2/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL27933757 0.85 LMNA (0.50) KDM4ETHRBTDP1KMT2AP2RX7
Ether SCHEMBL6687627 0.85 CYP2A6 (0.50) KMT2ANPC1HPGDRAB9AGAA
SCHEMBL231632 0.80
Ether SCHEMBL391384 0.78 ALDH1A1 (0.48) KDM4EKMT2ANPC1HPGDRAB9A
1,4-Dichlorobenzene SCHEMBL10839178 0.77 CYP2A6 (0.61) DRD4TDP1KMT2ANPC1RAB9A
SCHEMBL197605 0.77
Ether SCHEMBL28180268 0.76 CES2 (0.46) DRD4KDM4ETHRBTDP1KMT2A
Ether SCHEMBL8472514 0.76 ALDH1A1 (0.65) DRD4TDP1KMT2ANPC1HPGD
Bromobenzene SCHEMBL5103436 0.76 ALDH1A1 (0.55) TDP1KMT2ANPC1HPGDRAB9A
Methyl Alcohol SCHEMBL27601464 0.75 CYP2A6 (0.50) DRD4KMT2ALMNAHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3539968-B1 NOVEL TRITYL PROTECTING AGENT SEKISUI MEDICAL CO LTD (JP) 2021-07-14 EP disclosed