Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 3/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363692 | 0.84 | POLB (0.48) | L3MBTL1KMT2ATDP1CASP3SENP8 | |
| SCHEMBL2185979 | 0.81 | P2RX7 (0.39) | L3MBTL1NPC1GLAKMT2ATDP1 | |
| SCHEMBL2363363 | 0.81 | CES2 (0.41) | L3MBTL1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL2362641 | 0.75 | RAB9A (0.41) | L3MBTL1NPC1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9244293 | 0.73 | AKR1C3 (0.44) | L3MBTL1KMT2AALDH1A1GAALMNA | |
| SCHEMBL5195782 | 0.72 | CYP3A4 (0.33) | ALDH1A1 | |
| SCHEMBL2289029 | 0.72 | CAPN1 (0.37) | L3MBTL1TSHRKMT2AALDH1A1HTT | |
| SCHEMBL2295910 | 0.72 | HTT (0.51) | L3MBTL1NPC1KMT2AALDH1A1HTT | |
| SCHEMBL16670075 | 0.72 | RAB9A (0.40) | NPC1KMT2ACASP3SENP7HTT | |
| SCHEMBL2356948 | 0.71 | PRSS1 (0.42) | L3MBTL1TSHRKMT2ATDP1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
| EP-1960518-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067559-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | NAPRT 2841/4885L3MBTL1 297/4885TSHR 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.