Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027320 | 0.94 | ELANE (0.44) | PRSS1CTSGCTRB1CMA1LMNA | |
| SCHEMBL9318015 | 0.86 | LMNA (0.56) | PRSS1CTSGCTRB1CMA1LMNA | |
| SCHEMBL9244293 | 0.85 | AKR1C3 (0.44) | PRSS1CTSGCTRB1CMA1LMNA | |
| SCHEMBL8581687 | 0.84 | PTPN2 (0.36) | — | |
| SCHEMBL16670075 | 0.84 | RAB9A (0.40) | LMNAKMT2AMAPK1MAPTRAB9A | |
| SCHEMBL15485653 | 0.84 | LMNA (0.54) | PRSS1CTSGCTRB1CMA1LMNA | |
| Water SCHEMBL21440321 | 0.84 | LMNA (0.54) | PRSS1CTSGCTRB1CMA1LMNA | |
| SCHEMBL27192192 | 0.84 | LMNA (0.54) | PRSS1CTSGCTRB1CMA1LMNA | |
| SCHEMBL11207842 | 0.83 | LMNA (0.50) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL5986576 | 0.82 | CES2 (0.44) | LMNAKMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
| EP-1960518-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067559-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-06-14 | — | — | WO | disclosed |
| EP-0722458-B1 | PERALKYLATED OLIGOPEPTIDE MIXTURES | TORREY PINES INST (US) | 2002-04-03 | — | — | EP | disclosed |
| US-6287787-B1 | OLIGOPEPTIDE CHAINS OF A FIRST OLIGOPEPTIDE PORTION ARE BONDED BY A DISULFIDE BOND TO THE OLIGOPEPTIDE CHAINS OF A SECOND OLIGOPEPTIDE MIXTURE PORTION | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2001-09-11 | — | — | US | disclosed |
| EP-0710245-B1 | LINEAR SUBSTITUTED OLIGOALKYLENEIMINE LIBRARIES | TORREY PINES INST (US) | 2001-03-14 | — | — | EP | disclosed |
| US-6197529-B1 | MIXTURE OF EQUIMOLAR AMOUNTS OF CHAIN MEMBERS CONTAINING SAME NUMBER OF TWO TO TEN ALKYLENEIMINE REPEATING UNITS IN EACH, EACH UNIT HAS REDUCED AMINO ACID SIDE CHAIN BONDED TO THE CARBON ATOM ALPHA TO THE NITROGEN ATOM; DRUG SCREENING | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2001-03-06 | — | — | US | disclosed |
| EP-0722458-A4 | PERALKYLATED OLIGOPEPTIDE MIXTURES | TORREY PINES INST (US) | 1999-05-19 | — | — | EP | disclosed |
| EP-0558671-B1 | SYNTHESIS OF EQUIMOLAR MULTIPLE OLIGOMER MIXTURES, ESPECIALLY OF OLIGOPEPTIDE MIXTURES | ITEREX PHARMA LP (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0710245-A1 | LINEAR SUBSTITUTED OLIGOALKYLENEIMINE LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1996-05-08 | — | — | EP | disclosed |
| US-5504190-A | Equimolar multiple oligomer mixtures, especially oligopeptide mixtures | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0710245-A4 | LINEAR SUBSTITUTED OLIGOALKYLENEIMINE LIBRARIES | TORREY PINES INST (US) | 1996-03-12 | — | — | EP | disclosed |
| US-5480971-A | Peralkylated oligopeptide mixtures | HOUGHTEN PHARMACEUTICALS, INC. (US) | 1996-01-02 | — | — | US | disclosed |
| WO-1995014929-A1 | DIMERIC OLIGOPEPTIDE MIXTURE SETS | HOUGHTEN PHARMACEUTICALS, INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| WO-1995000539-A1 | PERALKYLATED OLIGOPEPTIDE MIXTURES | HOUGHTEN PHARMACEUTICALS, INC. (US) | 1995-01-05 | — | — | WO | disclosed |
| WO-1994026775-A1 | LINEAR SUBSTITUTED OLIGOALKYLENEIMINE LIBRARIES | HOUGHTEN PHARMACEUTICALS, INC. (US) | 1994-11-24 | — | — | WO | disclosed |
| EP-0558671-A4 | SYNTHESIS OF EQUIMOLAR MULTIPLE OLIGOMER MIXTURES, ESPECIALLY OF OLIGOPEPTIDE MIXTURES | ITEREX PHARMA LP (US) | 1994-05-11 | — | — | EP | disclosed |
| EP-0558671-A1 | SYNTHESIS OF EQUIMOLAR MULTIPLE OLIGOMER MIXTURES, ESPECIALLY OF OLIGOPEPTIDE MIXTURES | ITEREX PHARMACEUTICALS LTD. PARTNERSHIP (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009300-A1 | SYNTHESIS OF EQUIMOLAR MULTIPLE OLIGOMER MIXTURES, ESPECIALLY OF OLIGOPEPTIDE MIXTURES | ITEREX PHARMACEUTICALS LTD. PARTNERSHIP (US) | 1992-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | PRSS1 2323/4885CTSG 1102/4885CTRB1 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.