Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27876765 | 0.95 | CYP1A2 (0.40) | CYP3A4CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL10366084 | 0.87 | GLA (0.35) | CYP3A4CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL797702 | 0.81 | — | — | |
| SCHEMBL27791940 | 0.74 | TYMP (0.44) | MAPTHCAR2MEN1HTTKMT2A | |
| SCHEMBL658444 | 0.73 | USP2 (0.55) | CYP3A4CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL4372160 | 0.72 | PARP1 (0.38) | MAPTGPR84HCAR2ALOX15HCAR3 | |
| SCHEMBL25530345 | 0.72 | USP2 (0.53) | CYP3A4CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL26432247 | 0.72 | USP2 (0.53) | CYP3A4CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL18649060 | 0.72 | USP2 (0.53) | CYP3A4CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL8138860 | 0.71 | UTS2R (0.43) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536487-A | 5- (hetero) arylpyridazinones and their use as herbicides | 拜耳作物科学股份公司 | 2017-03-22 | — | — | CN | claimed |
| CN-106458927-A | 2-(hetero)aryl-pyridazinones and their use as herbicides | 拜耳作物科学股份公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106316962-A | 3-aryl pyridazinone compound, preparation method, pesticide composition and application | 中国科学院上海有机化学研究所 | 2017-01-11 | — | — | CN | claimed |
| EP-4076456-B1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | UNIV STRASBOURG (FR) | 2024-05-01 | — | — | EP | disclosed |
| EP-4077310-B1 | SIGMA-1 RECEPTOR LIGANDS AND USES THEREOF | UNIV STRASBOURG (FR) | 2024-05-01 | — | — | EP | disclosed |
| US-20230076057-A1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2023-03-09 | — | — | US | disclosed |
| US-20230049619-A1 | SIGMA-1 RECEPTOR LIGANDS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2023-02-16 | — | — | US | disclosed |
| EP-4076456-A1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | Université de Strasbourg (FR) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021123145-A1 | SIGMA-1 RECEPTOR LIGANDS AND USES THEREOF | UNIVERSITE DE STRASBOURG (FR) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021123174-A1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | UNIVERSITE DE STRASBOURG (FR) | 2021-06-24 | — | — | WO | disclosed |
| CN-109906082-A | Use the combined therapy of immune DASH inhibitor and PGE2 antagonist | 塔夫茨大学信托人 | 2019-06-18 | — | — | CN | disclosed |
| EP-1636233-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Pfizer Products Inc. (US) | 2006-03-22 | — | — | EP | disclosed |
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2004108728-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2004-12-16 | — | — | WO | disclosed |
| US-20040248881-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC | 2004-12-09 | — | — | US | disclosed |
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |
| US-4177273-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | SANDOZ, INC. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4004009-A | Antihypertensive aryl pyrazolo[4,3-c]pyridazinones | SANDOZ, INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-4004009-A | Antihypertensive aryl pyrazolo[4,3-c]pyridazinones | SANDOZ, INC. (US) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248881-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | CYP3A4 2204/4885CYP1A2 1245/4885CYP2D6 1698/4885 |
| US-20230076057-A1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | SIGMAR1, OPRL1, TMEM97 | CYP3A4 1857/4885CYP1A2 1009/4885CYP2D6 1746/4885 |
| US-20230049619-A1 | SIGMA-1 RECEPTOR LIGANDS AND USES THEREOF | SIGMAR1, TMEM97, OPRL1 | CYP3A4 1818/4885CYP1A2 942/4885CYP2D6 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.