Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 10/20 | 0.51 |
| ▸ | ANPEP | P15144 | 2/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748927 | 0.86 | MMP13 (0.59) | ALDH1A1KMT2AMMP2ANPEPMMP1 | |
| SCHEMBL23630362 | 0.86 | KMT2A (0.59) | ALDH1A1KMT2AMMP2ANPEPMMP1 | |
| SCHEMBL541907 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KMT2AMMP2ANPEPPOLB | |
| SCHEMBL541908 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KMT2AMMP2ANPEPPOLB | |
| SCHEMBL29948324 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KMT2AMMP2ANPEPPOLB | |
| SCHEMBL1734641 | 0.82 | MMP2 (0.68) | ALDH1A1KMT2AMMP2ANPEPMMP1 | |
| SCHEMBL1734643 | 0.82 | MMP2 (0.68) | ALDH1A1KMT2AMMP2ANPEPMMP1 | |
| SCHEMBL23630340 | 0.81 | KMT2A (0.56) | ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL23630346 | 0.81 | MMP2 (0.59) | ALDH1A1KMT2AMMP2ANPEPMMP1 | |
| SCHEMBL6432530 | 0.80 | MMP2 (0.57) | ALDH1A1KMT2AMMP2ANPEPMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087651-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | claimed |
| WO-2021141506-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | claimed |
| EP-4087651-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | disclosed |
| WO-2021141506-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | disclosed |