Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.38 |
| ▸ | TESK1 | Q15569 | 3/20 | 0.38 |
| ▸ | TESK2 | Q96S53 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17755588 | 0.77 | PIM1 (0.45) | CYP1A2PIM1CYP2A6HTTRECQL | |
| SCHEMBL8617736 | 0.77 | CYP2D6 (0.43) | CYP1A2PIM1CYP2A6HTTRECQL | |
| SCHEMBL28191914 | 0.72 | PIK3R2 (0.44) | HTTRECQLGAATDP1NPC1 | |
| SCHEMBL3612264 | 0.72 | KDM4E (0.55) | CYP1A2HTTCCR1CCR5CCR8 | |
| SCHEMBL29633944 | 0.72 | KDM4E (0.55) | CYP1A2HTTCCR1CCR5CCR8 | |
| SCHEMBL29454745 | 0.71 | NISCH (0.50) | CYP1A2PIM1HTTRECQLNPC1 | |
| SCHEMBL78566 | 0.71 | NISCH (0.50) | CYP1A2PIM1HTTRECQLNPC1 | |
| SCHEMBL29598957 | 0.71 | NISCH (0.50) | CYP1A2PIM1HTTRECQLNPC1 | |
| SCHEMBL18471236 | 0.71 | CYP1A2 (0.44) | CYP1A2PIM1CYP2A6HTTRECQL | |
| SCHEMBL26577328 | 0.70 | NOS3 (0.43) | GAACCR1CCR5CCR8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576039-B1 | CATALYTIC DEPOLYMERIZATION OF POLYMERS CONTAINING ELECTROPHILIC LINKAGES USING NUCLEOPHILIC REAGENTS | IBM (US) | 2011-08-03 | — | — | EP | disclosed |
| US-7544800-B2 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2009-06-09 | — | — | US | disclosed |
| US-7250510-B2 | Transition metal complexes of N-heterocyclic carbenes, method of preparation and use in transition metal catalyzed organic transformations | TOTAL SYNTHESIS, LTD. (CA) | 2007-07-31 | — | — | US | disclosed |
| US-7250510-B2 | Transition metal complexes of N-heterocyclic carbenes, method of preparation and use in transition metal catalyzed organic transformations | TOTAL SYNTHESIS, LTD. (CA) | 2007-07-31 | — | — | US | disclosed |
| US-20070073055-A1 | Transition metal complexes of N-heterocyclic carbenes, method of preparation and use in transition metal catalyzed organic transformations | TOTAL SYNTHESIS, LTD. (CA) | 2007-03-29 | — | — | US | disclosed |
| US-20070073055-A1 | Transition metal complexes of N-heterocyclic carbenes, method of preparation and use in transition metal catalyzed organic transformations | TOTAL SYNTHESIS, LTD. (CA) | 2007-03-29 | — | — | US | disclosed |
| US-7053221-B2 | Heteroatom-stabilized carbenes and precursors thereto as depolymerization catalysts | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2006-05-30 | — | — | US | disclosed |
| US-20050288508-A1 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2005-12-29 | — | — | US | disclosed |
| EP-1576039-A2 | CATALYTIC DEPOLYMERIZATION OF POLYMERS CONTAINING ELECTROPHILIC LINKAGES USING NUCLEOPHILIC REAGENTS | International Business Machines Corporation (US) | 2005-09-21 | — | — | EP | disclosed |
| US-6916936-B2 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2005-07-12 | — | — | US | disclosed |
| US-6911546-B2 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2005-06-28 | — | — | US | disclosed |
| US-20050049418-A1 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | HEDRICK JAMES LUPTON (US) | 2005-03-03 | — | — | US | disclosed |
| WO-2004060987-A2 | CATALYTIC DEPOLYMERIZATION OF POLYMERS CONTAINING ELECTROPHILIC LINKAGES USING NUCLEOPHILIC REAGENTS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20040127720-A1 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | NATIONAL SCIENCE FOUNDATION | 2004-07-01 | — | — | US | disclosed |
| US-20040127744-A1 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | NATIONAL SCIENCE FOUNDATION | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288508-A1 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | POLL, PNKP, PARN | CYP1A2 2496/4885PIM1 1354/4885CYP2A6 4415/4885 |
| US-20050049418-A1 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | POLL, PNKP, PARN | CYP1A2 2496/4885PIM1 1354/4885CYP2A6 4415/4885 |
| US-20040127744-A1 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | POLL, PNKP, PARP1 | CYP1A2 2467/4885PIM1 1508/4885CYP2A6 4376/4885 |
| US-20040127720-A1 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | POLL, PNKP, PARP1 | CYP1A2 2467/4885PIM1 1508/4885CYP2A6 4376/4885 |
| US-20070073055-A1 | Transition metal complexes of N-heterocyclic carbenes, method of preparation and use in transition metal catalyzed organic transformations | NDC1, NBAS, NUDC | CYP1A2 102/4885PIM1 1288/4885CYP2A6 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.