Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | DBH | P09172 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KAT7 | O95251 | 4/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.46 |
| ▸ | KAT6B | Q8WYB5 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31172576 | 0.78 | HTR2A (0.46) | ALDH1A1HTTMAPTKAT7KAT6A | |
| SCHEMBL8226215 | 0.78 | HDAC1 (0.48) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL23631796 | 0.78 | HTT (0.54) | ALDH1A1HTTMAPTGAAUSP2 | |
| SCHEMBL10066968 | 0.77 | KMT2A (0.56) | ALDH1A1HTTMAPTGAAUSP2 | |
| SCHEMBL3809589 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HTTDBHL3MBTL1HDAC1 | |
| SCHEMBL28825607 | 0.76 | GAA (0.47) | HTTMAPTGAAUSP2PDE4B | |
| SCHEMBL31172640 | 0.76 | HTT (0.56) | ALDH1A1HTTMAPTGAAUSP2 | |
| SCHEMBL23292578 | 0.76 | KAT7 (0.43) | ALDH1A1HTTMAPTGAAUSP2 | |
| SCHEMBL3319825 | 0.75 | MAPT (0.55) | ALDH1A1HTTMAPTGAAUSP2 | |
| SCHEMBL554165 | 0.75 | MEN1 (0.49) | ALDH1A1HTTMAPTGAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240277683-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2024-08-22 | — | — | US | disclosed |
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-20210213004-A1 | Compounds | CTXT PTY LTD (AU) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277683-A1 | COMPOUNDS | SLC10A1, ABCB11, REN | ALDH1A1 951/4885HTT 1154/4885DBH 1572/4885 |
| US-20210213004-A1 | Compounds | SLC10A1, ABCB11, REN | ALDH1A1 744/4885HTT 1181/4885DBH 1388/4885 |
| US-11911372-B2 | Compounds | SLC10A1, ABCB11, REN | ALDH1A1 744/4885HTT 1181/4885DBH 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.