Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KAT7 | O95251 | 5/20 | 0.49 |
| ▸ | KAT6B | Q8WYB5 | 5/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345848 | 0.89 | KMT2A (0.54) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL10053919 | 0.84 | MEN1 (0.50) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL10022368 | 0.81 | L3MBTL1 (0.49) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL28853149 | 0.80 | ADRB2 (0.54) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL22031236 | 0.79 | L3MBTL1 (0.53) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL4354266 | 0.79 | HTT (0.56) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL22031238 | 0.78 | L3MBTL1 (0.54) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL554165 | 0.78 | MEN1 (0.49) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL23631850 | 0.77 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1L3MBTL1HTT | |
| SCHEMBL20069807 | 0.77 | L3MBTL1 (0.57) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006203-A1 | N-CYCLYL-3 - (CYCLYLCARBONYLAMINOMETHYL) BENZAMIDE DERIVATIVES AS RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |