SCHEMBL2363359

SCHEMBL2363359

CC(C)[Si](CCCNCCC[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.35
GLA P06280 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP1A2 P05177 1/20 0.33
CA12 O43570 1/20 0.30
CA2 P00918 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4238615 0.91 CA12 (0.48) CYP2C19ALDH1A1TSHRMEN1KMT2A
SCHEMBL3777409 0.82
SCHEMBL3776007 0.80
SCHEMBL19543082 0.79 HRH4 (0.35)
SCHEMBL3774562 0.79
SCHEMBL3777414 0.78
SCHEMBL3776011 0.76
SCHEMBL3772390 0.76
SCHEMBL3776375 0.76
SCHEMBL3777564 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10556918-B2 Method for preparing aminosilane-based compound LG CHEM, LTD. (KR) 2020-02-11 US claimed
EP-3330273-B1 NOVEL METHOD FOR PREPARING AMINOSILANE-BASED COMPOUND LG CHEMICAL LTD (KR) 2019-06-19 EP claimed
US-20180282353-A1 NOVEL METHOD FOR PREPARING AMINOSILANE-BASED COMPOUND LG CHEM, LTD. (KR) 2018-10-04 US claimed
EP-3330273-A2 NOVEL METHOD FOR PREPARING AMINOSILANE-BASED COMPOUND LG Chem, Ltd. (KR) 2018-06-06 EP claimed
US-9422409-B2 Method of hydrolytically stable bonding of elastomers to substrates MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-08-23 US claimed
US-20110195260-A1 METHOD OF HYDROLYTICALLY STABLE BONDING OF ELASTOMERS TO SUBSTRATES MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2011-08-11 US claimed
WO-2010042784-A2 METHOD OF HYDROLYTICALLY STABLE BONDING OF ELASTOMERS TO SUBSTRATES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-04-15 WO claimed
CN-109415539-B Aminosilane compound, method for producing same, and modified conjugated diene polymer containing compound 株式会社LG化学 2021-04-13 CN disclosed
US-10800862-B2 Amino silane-based compound, method of preparing the same, and modified conjugated diene-based polymer including the compound LG CHEM, LTD. (KR) 2020-10-13 US disclosed
US-10556918-B2 Method for preparing aminosilane-based compound LG CHEM, LTD. (KR) 2020-02-11 US disclosed
US-20190256617-A1 Amino Silane-Based Compound, Method of Preparing The Same, And Modified Conjugated Diene-Based Polymer Including The Compound LG CHEM, LTD. (KR) 2019-08-22 US disclosed
EP-3524638-A1 AMINOSILANE-BASED COMPOUND, PROCESS FOR PREPARING SAME, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPRISING SAME LG Chem, Ltd. (KR) 2019-08-14 EP disclosed
EP-3330273-B1 NOVEL METHOD FOR PREPARING AMINOSILANE-BASED COMPOUND LG CHEMICAL LTD (KR) 2019-06-19 EP disclosed
US-20180282353-A1 NOVEL METHOD FOR PREPARING AMINOSILANE-BASED COMPOUND LG CHEM, LTD. (KR) 2018-10-04 US disclosed
EP-3330273-A2 NOVEL METHOD FOR PREPARING AMINOSILANE-BASED COMPOUND LG Chem, Ltd. (KR) 2018-06-06 EP disclosed
US-9422409-B2 Method of hydrolytically stable bonding of elastomers to substrates MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-08-23 US disclosed
US-20110195260-A1 METHOD OF HYDROLYTICALLY STABLE BONDING OF ELASTOMERS TO SUBSTRATES MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2011-08-11 US disclosed
WO-2010042784-A2 METHOD OF HYDROLYTICALLY STABLE BONDING OF ELASTOMERS TO SUBSTRATES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10800862-B2 Amino silane-based compound, method of preparing the same, and modified conjugated diene-based polymer including the compound PRMT1, PRMT8, SKP2 CYP2C19 3651/4885ALDH1A1 732/4885TSHR 3130/4885
US-20190256617-A1 Amino Silane-Based Compound, Method of Preparing The Same, And Modified Conjugated Diene-Based Polymer Including The Compound PRMT1, PRMT8, SKP2 CYP2C19 3796/4885ALDH1A1 742/4885TSHR 3191/4885
US-20180282353-A1 NOVEL METHOD FOR PREPARING AMINOSILANE-BASED COMPOUND SRM, MSN, CAD CYP2C19 3350/4885ALDH1A1 2454/4885TSHR 4452/4885
US-10556918-B2 Method for preparing aminosilane-based compound SRM, CAD, MSN CYP2C19 2803/4885ALDH1A1 1924/4885TSHR 4442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.