SCHEMBL23633658

SCHEMBL23633658

c1ccc(Nc2cccc3c2ccc2c4ccccc4oc32)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.63
▸ GAA P10253 4/20 0.63
▸ MEN1 O00255 3/20 0.63
▸ KMT2A Q03164 3/20 0.63
▸ TDP1 Q9NUW8 2/20 0.63
▸ MAPT P10636 2/20 0.63
▸ GLA P06280 1/20 0.63
▸ RECQL P46063 1/20 0.63
▸ ALDH1A1 P00352 7/20 0.53
▸ HPGD P15428 5/20 0.53
▸ TSHR P16473 2/20 0.53
▸ HSD17B10 Q99714 2/20 0.53
▸ ALOX15 P16050 2/20 0.53
▸ ATM Q13315 2/20 0.53
▸ CDC25B P30305 2/20 0.53
▸ TP53 P04637 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ LMNA P02545 3/20 0.47
▸ CASP3 P42574 1/20 0.47
▸ SENP7 Q9BQF6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18646351 0.91 KDM4E (0.51) KDM4EGAAMEN1KMT2ATDP1
SCHEMBL2521923 0.90 KDM4E (0.57) KDM4EGAAMEN1KMT2ATDP1
SCHEMBL23168551 0.87 KDM4E (0.48) KDM4EGAAMEN1KMT2ATDP1
SCHEMBL17735238 0.84 ALOX5 (0.54) KDM4EGAAMEN1KMT2ATDP1
SCHEMBL23633638 0.83 ALDH1A1 (0.50) KDM4EGAAMEN1KMT2ATDP1
SCHEMBL23633537 0.82 KDM4E (0.61) KDM4EGAAMEN1KMT2ATDP1
SCHEMBL17463893 0.81 ALOX5 (0.51) KDM4EGAAMEN1KMT2ATDP1
SCHEMBL24826942 0.81 MAPK14 (0.48) KDM4EGAAMEN1KMT2ATDP1
SCHEMBL23239603 0.81 AKR1C3 (0.49) KDM4EGAAMEN1KMT2ATDP1
SCHEMBL14295749 0.81 AKR1C3 (0.49) KDM4EGAAMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371374-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-11-16 — — US disclosed
US-20230371374-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-11-16 — — US disclosed
US-11678577-B2 Organic electronic element comprising compound for organic electronic element and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-06-13 — — US disclosed
US-11678577-B2 Organic electronic element comprising compound for organic electronic element and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-06-13 — — US disclosed
US-20220131090-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2022-04-28 — — US disclosed
US-11063226-B1 Organic electronic element comprising compound for organic electronic element and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2021-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11678577-B2 Organic electronic element comprising compound for organic electronic element and an electronic device thereof ESR1, EML4, OCIAD2 KDM4E 764/4885GAA 2714/4885MEN1 958/4885
US-20230371374-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, TELO2, LIMS1 KDM4E 3228/4885GAA 449/4885MEN1 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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