Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19675614 | 0.80 | HTR2C (0.37) | NOTUMMAPTPOLBALDH1A1TSHR | |
| SCHEMBL23633844 | 0.79 | HTR2C (0.36) | NOTUMTSHRHTR2AHTR2CHTR2B | |
| SCHEMBL23633850 | 0.79 | HTR2C (0.39) | NOTUMTSHRHTR2AHTR2CHTR2B | |
| SCHEMBL23633824 | 0.79 | HTR2A (0.39) | NOTUMHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL20381958 | 0.78 | HTR2C (0.47) | NOTUMHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL24358930 | 0.77 | GAA (0.47) | ALDH1A1HTR2AHTR2CCYP1A2CYP3A4 | |
| SCHEMBL14531012 | 0.75 | XIAP (0.45) | ALDH1A1HRH3SLC22A12 | |
| SCHEMBL19115422 | 0.74 | HTR2C (0.37) | NOTUMHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL19675746 | 0.73 | ATAD2 (0.40) | NOTUMMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL19708000 | 0.72 | ALDH1A1 (0.40) | MAPTMEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11059977-B2 | Near-infrared-absorbing dye, optical filter, and imaging device | AGC Inc. (JP) | 2021-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059977-B2 | Near-infrared-absorbing dye, optical filter, and imaging device | CRY2, CRY1, LBR | NOTUM 550/4885MAPT 1332/4885POLB 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.