Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.39 |
| ▸ | AKT1 | P31749 | 16/20 | 0.39 |
| ▸ | MTOR | P42345 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635153 | 0.86 | F10 (0.37) | — | |
| SCHEMBL18979437 | 0.79 | PIK3CA (0.52) | PIK3CAAKT1MTOR | |
| SCHEMBL18979453 | 0.77 | PIK3CA (0.46) | PIK3CAAKT1MTOR | |
| SCHEMBL23635162 | 0.72 | DYRK1A (0.34) | — | |
| SCHEMBL23635155 | 0.70 | LDLR (0.38) | — | |
| SCHEMBL18996612 | 0.65 | DYRK1A (0.48) | — | |
| SCHEMBL17027812 | 0.65 | PIK3CA (0.68) | PIK3CAAKT1MTOR | |
| SCHEMBL24187480 | 0.64 | RAB9A (0.51) | — | |
| SCHEMBL17027809 | 0.63 | DYRK1A (0.42) | — | |
| SCHEMBL17027820 | 0.63 | TMEM97 (0.52) | PIK3CAAKT1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107909-B1 | ANTIMITOTIC AMIDES FOR THE TREATMENT OF CANCER AND PROLIFERATIVE DISORDERS | FROST BIOLOGIC INC (US) | 2021-07-14 | — | — | EP | disclosed |