SCHEMBL23635274

SCHEMBL23635274

CCCCCCCC(=O)Oc1ccc(CI)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
ALOX15 P16050 1/20 0.49
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
THRB P10828 2/20 0.48
THRA P10827 1/20 0.48
ESR1 P03372 2/20 0.47
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA2 P00918 2/20 0.44
BCL9 O00512 1/20 0.44
CTNNB1 P35222 1/20 0.44
HTR1A P08908 1/20 0.44
HTR1B P28222 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21470145 1.00 KMT2A (0.57) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL19925262 0.89 KMT2A (0.58) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL15549028 0.88 KMT2A (0.68) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL5696798 0.88 KMT2A (0.68) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL5696854 0.88 KMT2A (0.68) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL5696715 0.88 KMT2A (0.68) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL38661498 0.88 KMT2A (0.68) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL28366896 0.87 KMT2A (0.59) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL28371002 0.87 KMT2A (0.59) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL15987877 0.87 KMT2A (0.59) KMT2ASMN1; SMN2ALOX15NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265480-A1 METHOD FOR DETECTION OF MICROORGANISMS NEMIS TECH AG (CH) 2023-08-24 US disclosed
US-11649475-B2 Dioxetane compounds and their use for the detection of microorganisms RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-05-16 US disclosed
US-11649475-B2 Dioxetane compounds and their use for the detection of microorganisms RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-05-16 US disclosed
US-20210214766-A1 DIOXETANE COMPOUNDS AND THEIR USE FOR THE DETECTION OF MICROORGANISMS NEMIS TECHNOLOGIES AG (CH) 2021-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649475-B2 Dioxetane compounds and their use for the detection of microorganisms DAXX, LITAF, EDF1 KMT2A 3558/4885SMN1; SMN2 4855/4885ALOX15 413/4885
US-20210214766-A1 DIOXETANE COMPOUNDS AND THEIR USE FOR THE DETECTION OF MICROORGANISMS DAXX, CD14, MYADM KMT2A 3191/4885SMN1; SMN2 4827/4885ALOX15 539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.