Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635381 | 0.85 | SLC9A1 (0.38) | GRM2JAK2JAK1KDM4ELMNA | |
| SCHEMBL20564852 | 0.79 | LMNA (0.42) | GRM2KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL20565417 | 0.74 | KDM4E (0.38) | GRM2KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL23635382 | 0.72 | GRM2 (0.38) | GRM2KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL23635301 | 0.71 | C5AR1 (0.41) | GRM2KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL23635380 | 0.69 | GRM2 (0.44) | GRM2KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL23635338 | 0.69 | GPR119 (0.34) | KDM4ELMNAHPGDALDH1A1MAPT | |
| SCHEMBL23635303 | 0.67 | GRM2 (0.39) | GRM2KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL23635300 | 0.67 | KDM4E (0.35) | KDM4ELMNAHPGDALDH1A1MEN1 | |
| SCHEMBL23630458 | 0.67 | MAPT (0.41) | KDM4ELMNAHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |