Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635355 | 0.99 | KDM5A (0.42) | KDM5AALDH1A1HSD11B1HPGDMEN1 | |
| SCHEMBL23635387 | 0.98 | KDM5A (0.40) | KDM5AALDH1A1HSD11B1HPGDMEN1 | |
| SCHEMBL20565415 | 0.81 | CA12 (0.38) | ALDH1A1HPGDLMNAPLATKDM4E | |
| SCHEMBL20565504 | 0.81 | ADORA3 (0.37) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL23635367 | 0.79 | HSD11B1 (0.35) | ALDH1A1HSD11B1HPGDMEN1KMT2A | |
| SCHEMBL20565460 | 0.78 | MIF (0.36) | L3MBTL1PLAT | |
| SCHEMBL20564879 | 0.77 | MAPT (0.36) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL20565117 | 0.77 | FEN1 (0.36) | HSD11B1MEN1KMT2APLAT | |
| SCHEMBL23635332 | 0.76 | L3MBTL1 (0.35) | ALDH1A1HSD11B1HPGDMEN1KMT2A | |
| SCHEMBL20565532 | 0.75 | DDR1 (0.36) | ALDH1A1HSD11B1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |