Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635357 | 0.98 | KDM5A (0.42) | KDM5AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL23635355 | 0.97 | KDM5A (0.42) | KDM5AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20565504 | 0.81 | ADORA3 (0.37) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL20565415 | 0.81 | CA12 (0.38) | ALDH1A1LMNAHPGDPLATKDM4E | |
| SCHEMBL23635367 | 0.79 | HSD11B1 (0.35) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL20565460 | 0.78 | MIF (0.36) | L3MBTL1PLAT | |
| SCHEMBL20564879 | 0.77 | MAPT (0.36) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL20565117 | 0.77 | FEN1 (0.36) | MEN1KMT2AHSD11B1PLAT | |
| SCHEMBL23635332 | 0.76 | L3MBTL1 (0.35) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL20565456 | 0.75 | PLAT (0.36) | LMNAHPGDHSD11B1PDE9APLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |