SCHEMBL23635720

SCHEMBL23635720

Cn1c(=O)cc(C(F)(F)F)n(C(F)F)c1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.37
ALDH1A1 P00352 4/20 0.37
PLA2G7 Q13093 1/20 0.37
GAA P10253 2/20 0.36
LMNA P02545 1/20 0.36
ALOX5 P09917 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
RECQL P46063 1/20 0.34
MAPT P10636 1/20 0.33
TSHR P16473 2/20 0.32
POLB P06746 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
AR P10275 2/20 0.31
PGR P06401 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5162572 0.79 RECQL (0.41) EGFRALDH1A1PLA2G7GAALMNA
SCHEMBL23664492 0.76 RECQL (0.36) EGFRALDH1A1PLA2G7GAALMNA
SCHEMBL23635722 0.75 ALDH1A1 (0.53) EGFRALDH1A1GAANPSR1L3MBTL1
SCHEMBL21500471 0.75 ADORA2B (0.34) ALDH1A1PLA2G7AR
SCHEMBL20693127 0.74 ALDH1A1 (0.44) EGFRALDH1A1GAANPSR1AR
SCHEMBL23635719 0.70 AR (0.36) EGFRALDH1A1GAALMNARECQL
SCHEMBL20693125 0.70 ADORA2B (0.40) EGFRALDH1A1GAARECQLAR
SCHEMBL20693128 0.67 SMN1; SMN2 (0.41) ALDH1A1GAALMNARECQLMAPT
SCHEMBL25061427 0.66 ALDH1A1 (0.34) ALDH1A1GAAMAPTHSD17B10
SCHEMBL25061495 0.66 ALDH1A1 (0.34) ALDH1A1GAAMAPTHSD17B10AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021143677-A1 FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF 青岛清原化合物有限公司 2021-07-22 WO disclosed
WO-2021139482-A1 CARBOXYLIC ACID DERIVATIVE-SUBSTITUTED IMINO ARYL COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2021-07-15 WO disclosed