Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23664492 | 0.83 | RECQL (0.36) | RECQLEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL24960586 | 0.80 | KMT2A (0.36) | KMT2A | |
| SCHEMBL20870875 | 0.80 | RECQL (0.32) | RECQLEGFRALDH1A1LMNAGAA | |
| SCHEMBL17083422 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL23635700 | 0.79 | GAA (0.32) | RECQLEGFRALDH1A1LMNAGAA | |
| SCHEMBL23635720 | 0.79 | EGFR (0.37) | RECQLEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL21500471 | 0.79 | ADORA2B (0.34) | ALDH1A1PLA2G7 | |
| SCHEMBL21500523 | 0.79 | — | — | |
| SCHEMBL23635722 | 0.79 | ALDH1A1 (0.53) | EGFRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL20693127 | 0.77 | ALDH1A1 (0.44) | EGFRALDH1A1GAAMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150592-A2 | N3-SUBSTITUTED URACIL COMPOUNDS AS TRPA1 INHIBITORS | D.E. SHAW RESEARCH, LLC (US) | 2023-08-10 | — | — | WO | disclosed |
| EP-4177250-A1 | PREPARATION METHOD FOR PHENYLISOXAZOLINE COMPOUND | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2023-05-10 | — | — | EP | disclosed |
| EP-3658551-B1 | BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES | REDAG CROP PROT LTD (GB) | 2022-01-19 | — | — | EP | disclosed |
| US-20210337797-A1 | PREPARATION OF PYRIDAZINYL AMINE COMPOUND AND APPLICATION THEREOF | Synwill Co., Ltd. (CN) | 2021-11-04 | — | — | US | disclosed |
| EP-3858829-A1 | METHOD FOR PREPARING ISOXAZOLINE-CONTAINING URACIL COMPOUND BY METHYLATION | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| EP-3854791-A1 | PREPARATION OF PYRIDAZINYL AMINE COMPOUND AND APPLICATION THEREOF | Synwill Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |
| WO-2021143677-A1 | FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF | 青岛清原化合物有限公司 | 2021-07-22 | — | — | WO | disclosed |
| WO-2021139498-A1 | ISOXAZOLINE OXIME CARBOXYLATE COMPOUND, PREPARATION METHOD THEREFOR, AND HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2021-07-15 | — | — | WO | disclosed |
| WO-2021139482-A1 | CARBOXYLIC ACID DERIVATIVE-SUBSTITUTED IMINO ARYL COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2021-07-15 | — | — | WO | disclosed |
| WO-2019062802-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USES IN AGRICULTURE RELATED APPLICATION | DONGGUAN HEC TECH R & D CO., LTD. (CN) | 2019-04-04 | — | — | WO | disclosed |
| US-7368413-B2 | Herbicidal composition and method of using the same | NIHON NOHYAKU CO., LTD. (JP) | 2008-05-06 | — | — | US | disclosed |
| US-7368413-B2 | Herbicidal composition and method of using the same | NIHON NOHYAKU CO., LTD. (JP) | 2008-05-06 | — | — | US | disclosed |
| US-7232926-B2 | Method for the production of sulphamic acid halogenides | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |
| US-7232926-B2 | Method for the production of sulphamic acid halogenides | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |
| EP-1237878-B1 | 4-PYRIMIDINYL-N-ACYL-L-PHENYLALANINES | HOFFMANN LA ROCHE (CH) | 2007-03-21 | — | — | EP | disclosed |
| EP-1237878-B1 | 4-PYRIMIDINYL-N-ACYL-L-PHENYLALANINES | HOFFMANN LA ROCHE (CH) | 2007-03-21 | — | — | EP | disclosed |
| EP-1743527-A2 | herbicides based on substituted carboxylic acid anilides | Bayer CropScience Aktiengesellschaft (DE) | 2007-01-17 | — | — | EP | disclosed |
| EP-1237878-A2 | 4-PYRIMIDINYL-N-ACYL-L-PHENYLALANINES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-09-11 | — | — | EP | disclosed |
| US-6380387-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS | HOFFMANN-LA ROCHE INC. | 2002-04-30 | — | — | US | disclosed |
| WO-2001042225-A2 | 4-PYRIMIDINYL-N-ACYL-L-PHENYLALANINES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210337797-A1 | PREPARATION OF PYRIDAZINYL AMINE COMPOUND AND APPLICATION THEREOF | ACHE, EML4, TOP2A | RECQL 31/4885EGFR 362/4885MEN1 1758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.