SCHEMBL20693128

SCHEMBL20693128

COC(=O)Cn1c(C(F)(F)F)cc(=O)n(C)c1=O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.41
KDM4E B2RXH2 4/20 0.41
MAPT P10636 2/20 0.40
KAT2B Q92831 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 4/20 0.38
GAA P10253 3/20 0.37
HSD17B10 Q99714 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
RECQL P46063 1/20 0.37
LMNA P02545 2/20 0.36
ALOX15 P16050 1/20 0.36
HTT P42858 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2B Q13224 1/20 0.36
POLQ O75417 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23635722 0.77 ALDH1A1 (0.53) KDM4EMEN1KMT2AALDH1A1GAA
SCHEMBL20693127 0.75 ALDH1A1 (0.44) ALDH1A1GAANPSR1
SCHEMBL20693125 0.72 ADORA2B (0.40) ALDH1A1GAARECQL
SCHEMBL23664492 0.71 RECQL (0.36) SMN1; SMN2MAPTMEN1KMT2AALDH1A1
SCHEMBL5162572 0.70 RECQL (0.41) SMN1; SMN2KDM4EMAPTMEN1KMT2A
SCHEMBL24703554 0.68 KDM4E (0.57) SMN1; SMN2KDM4EMAPTKAT2BMEN1
SCHEMBL23635720 0.67 EGFR (0.37) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL8780843 0.66 MAPT (0.49) SMN1; SMN2MAPTKMT2AALDH1A1HSD17B10
SCHEMBL29456293 0.65 MAPK9 (0.52) SMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL3783019 0.65 MAPK9 (0.52) SMN1; SMN2KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3658551-B1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES REDAG CROP PROT LTD (GB) 2022-01-19 EP disclosed
WO-2019020987-A1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES REDAG CROP PROTECTION LTD. (GB) 2019-01-31 WO disclosed