SCHEMBL23635828

SCHEMBL23635828

CCOC(=O)c1cc(OC)ccc1F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.56
ALDH1A1 P00352 5/20 0.56
KDM4E B2RXH2 4/20 0.56
CA12 O43570 3/20 0.53
CA2 P00918 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
MAOB P27338 2/20 0.53
GLA P06280 1/20 0.53
CA3 P07451 1/20 0.53
GAA P10253 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
PRKCZ Q05513 1/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
LMNA P02545 2/20 0.50
HTT P42858 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20267591 0.88 ALDH1A1 (0.51) HPGDALDH1A1KDM4EGAALMNA
SCHEMBL12093644 0.87 KDM4E (0.56) HPGDALDH1A1KDM4ECA12CA2
SCHEMBL28404718 0.87 KAT6A (0.51) ALDH1A1KDM4ECA12CA2CA7
SCHEMBL28275232 0.85 HPGD (0.60) HPGDALDH1A1KDM4ECA12CA2
SCHEMBL28791799 0.84 TSHR (0.46) HPGDALDH1A1KDM4ECA12CA2
SCHEMBL3481145 0.83 HPGD (0.58) HPGDALDH1A1KDM4ECA12CA2
SCHEMBL12093159 0.83 CA12 (0.70) CA12CA2CA7CA9CA14
SCHEMBL2258923 0.83 KDM4E (0.60) ALDH1A1KDM4ECA12CA2CA7
SCHEMBL29191709 0.82 MEN1 (0.62) HPGDALDH1A1KDM4ECA12CA2
SCHEMBL2709952 0.82 CA12 (0.73) HPGDALDH1A1KDM4ECA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277683-A1 COMPOUNDS CTXT PTY LTD (AU) 2024-08-22 US disclosed
US-11911372-B2 Compounds CTXT PTY LTD (AU) 2024-02-27 US disclosed
US-11911372-B2 Compounds CTXT PTY LTD (AU) 2024-02-27 US disclosed
US-11911372-B2 Compounds CTXT PTY LTD (AU) 2024-02-27 US disclosed
US-20210213004-A1 Compounds CTXT PTY LTD (AU) 2021-07-15 US disclosed
CN-1425008-A 3-aminoquinazolin-2, 4-dione antibacterial agents WARNER LAMBERT CO (US) 2003-06-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277683-A1 COMPOUNDS SLC10A1, ABCB11, REN HPGD 1495/4885ALDH1A1 951/4885KDM4E 4246/4885
US-20210213004-A1 Compounds SLC10A1, ABCB11, REN HPGD 1882/4885ALDH1A1 744/4885KDM4E 3932/4885
US-11911372-B2 Compounds SLC10A1, ABCB11, REN HPGD 1882/4885ALDH1A1 744/4885KDM4E 3932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.