Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842116 | 1.00 | KDM4E (0.47) | KDM4EHSD17B10RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23635873 | 0.85 | KDM4E (0.54) | KDM4EHSD17B10RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23631832 | 0.84 | GLS (0.46) | KDM4EHSD17B10RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23635907 | 0.81 | KDM4E (0.50) | KDM4EHSD17B10RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30842170 | 0.81 | KDM4E (0.50) | KDM4EHSD17B10RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23631831 | 0.74 | TDP1 (0.37) | KDM4EHSD17B10RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23631787 | 0.72 | KDM4E (0.48) | KDM4EHSD17B10RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23635964 | 0.72 | KAT7 (0.53) | KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL30842121 | 0.71 | KDM4E (0.53) | KDM4EHSD17B10RAB9ASMN1; SMN2HPGD | |
| SCHEMBL27097750 | 0.71 | KDM4E (0.53) | KDM4EHSD17B10RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-20210213004-A1 | Compounds | CTXT PTY LTD (AU) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210213004-A1 | Compounds | SLC10A1, ABCB11, REN | KDM4E 3932/4885HSD17B10 412/4885RAB9A 323/4885 |
| US-11911372-B2 | Compounds | SLC10A1, ABCB11, REN | KDM4E 3932/4885HSD17B10 412/4885RAB9A 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.