Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842170 | 1.00 | KDM4E (0.50) | KDM4EHSD17B10HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23631847 | 0.88 | KDM4E (0.52) | KDM4EHSD17B10HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23635969 | 0.81 | KDM4E (0.47) | KDM4EHSD17B10HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL30842116 | 0.81 | KDM4E (0.47) | KDM4EHSD17B10HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23292496 | 0.78 | HTT (0.43) | KDM4EHSD17B10HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23292511 | 0.78 | ALDH1A1 (0.54) | KDM4EHSD17B10HPGDALDH1A1MEN1 | |
| SCHEMBL23635952 | 0.78 | KAT7 (0.58) | KAT7KAT6BKAT6A | |
| SCHEMBL27097771 | 0.77 | KDM4E (0.56) | KDM4EHSD17B10HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23635944 | 0.75 | KDM4E (0.53) | KDM4EHSD17B10HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28867909 | 0.73 | TSHR (0.70) | HSD17B10HPGDRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-20210213004-A1 | Compounds | CTXT PTY LTD (AU) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210213004-A1 | Compounds | SLC10A1, ABCB11, REN | KDM4E 3932/4885HSD17B10 412/4885HPGD 1882/4885 |
| US-11911372-B2 | Compounds | SLC10A1, ABCB11, REN | KDM4E 3932/4885HSD17B10 412/4885HPGD 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.