SCHEMBL236360

SCHEMBL236360

[O]CC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 5/20 0.52
GRIN3B O60391 5/20 0.52
GRIN1 Q05586 5/20 0.52
GRIN2A Q12879 5/20 0.52
GRIN2B Q13224 5/20 0.52
GRIN2C Q14957 5/20 0.52
GRIN3A Q8TCU5 5/20 0.52
ALDH1A1 P00352 4/20 0.44
TSHR P16473 2/20 0.44
EPHX2 P34913 5/20 0.41
HSD17B10 Q99714 1/20 0.40
BPTF Q12830 1/20 0.40
SLC22A2 O15244 1/20 0.38
SLC22A1 O15245 1/20 0.38
LMNA P02545 1/20 0.38
NFKB1 P19838 1/20 0.38
STAT6 P42226 1/20 0.38
SLC47A1 Q96FL8 1/20 0.38
SIGMAR1 Q99720 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237473 0.77 GRIN2D (0.56) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1558865 0.75 GRIN2D (0.52) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7259186 0.73 GRIN2D (0.58) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11697939 0.73 GRIN2D (0.68) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1558863 0.71 GRIN2D (0.56) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL17969194 0.71
SCHEMBL339412 0.69 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL197070 0.69 GRIN2D (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL159995 0.69 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL13569745 0.69 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3966870-B1 AROMATIC COMPOUNDS MERCK PATENT GMBH (DE) 2024-04-03 EP claimed
US-20220238816-A1 AROMATIC COMPOUNDS MERCK PATENT GMBH (DE) 2022-07-28 US claimed
CN-113812003-A Aromatic compound 默克专利有限公司 2021-12-17 CN claimed
WO-2020225398-A1 AROMATIC COMPOUNDS MERCK PATENT GMBH (DE) 2020-11-12 WO claimed
US-20150338736-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM AND METHOD OF FORMING PATTERN FUJIFILM CORPORATION (JP) 2015-11-26 US claimed
WO-2014104400-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM AND METHOD OF FORMING PATTERN FUJIFILM CORPORATION (JP) 2014-07-03 WO claimed
EP-0675899-B1 NOVEL INHIBITORS OF FACTOR Xa CORVAS INT INC (US) 1999-03-17 EP claimed
US-5883077-A PEPTIDES ALDEHYDE ANALOGUES CORVAS INTERNATIONAL, INC. (US) 1999-03-16 US claimed
US-5739112-A ANTICOAGULANTS CORVAS INTERNATIONAL, INC. (US) 1998-04-14 US claimed
EP-0675899-A4 NOVEL INHIBITORS OF FACTOR Xa. CORVAS INT INC (US) 1996-01-24 EP claimed
EP-0675899-A1 NOVEL INHIBITORS OF FACTOR Xa CORVAS INTERNATIONAL, INC. (US) 1995-10-11 EP claimed
WO-1994013693-A1 NOVEL INHIBITORS OF FACTOR Xa CORVAS INTERNATIONAL, INC. (US) 1994-06-23 WO claimed
CN-117908332-A Composition for forming resist underlayer film containing radical scavenger 日产化学株式会社 2024-04-19 CN disclosed
EP-3966870-B1 AROMATIC COMPOUNDS MERCK PATENT GMBH (DE) 2024-04-03 EP disclosed
CN-113383036-B Composition for forming resist underlayer film containing radical scavenger 日产化学株式会社 2024-02-23 CN disclosed
CN-116783552-A Resist underlayer film forming composition containing polymer having alicyclic hydrocarbon group 日产化学株式会社 2023-09-19 CN disclosed
EP-0675899-A4 NOVEL INHIBITORS OF FACTOR Xa. CORVAS INT INC (US) 1996-01-24 EP disclosed
EP-0675899-A1 NOVEL INHIBITORS OF FACTOR Xa CORVAS INTERNATIONAL, INC. (US) 1995-10-11 EP disclosed
US-5371072-A ANTICOAGULANTS CORVAS INTERNATIONAL, INC. (US) 1994-12-06 US disclosed
WO-1994013693-A1 NOVEL INHIBITORS OF FACTOR Xa CORVAS INTERNATIONAL, INC. (US) 1994-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338736-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM AND METHOD OF FORMING PATTERN AFF1, MACF1, RER1 GRIN2D 905/4885GRIN3B 1397/4885GRIN1 329/4885
US-20220238816-A1 AROMATIC COMPOUNDS CHRM1, CCNB1, H1-3 GRIN2D 525/4885GRIN3B 616/4885GRIN1 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.