Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 3/20 | 0.55 |
| ▸ | RORC | P51449 | 8/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23636838 | 0.91 | RORC (0.54) | WDR91RORCHDAC6SMYD3 | |
| SCHEMBL23636959 | 0.82 | RORC (0.40) | WDR91RORCUTS2RMAPTKMT2A | |
| SCHEMBL23636789 | 0.82 | WDR91 (0.48) | WDR91RORC | |
| SCHEMBL23632940 | 0.82 | PRKACA (0.54) | RORCPRKACACDK8GSK3AGSK3B | |
| SCHEMBL23632937 | 0.82 | PRKACA (0.54) | RORCPRKACACDK8GSK3AGSK3B | |
| SCHEMBL28581760 | 0.79 | RORC (0.49) | WDR91RORCMAPTKMT2AALDH1A1 | |
| SCHEMBL28581762 | 0.79 | RORC (0.49) | WDR91RORCMAPTKMT2AALDH1A1 | |
| SCHEMBL23636852 | 0.78 | RORC (0.52) | RORCHDAC6SMYD3MAPTKMT2A | |
| SCHEMBL23636636 | 0.76 | CYP1A2 (0.54) | RORCMAPTKMT2AALDH1A1HSD17B10 | |
| SCHEMBL21619504 | 0.76 | RORC (0.46) | WDR91RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139599-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |