Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23636762 | 0.91 | WDR91 (0.55) | RORCHDAC6WDR91SMYD3 | |
| SCHEMBL28581762 | 0.86 | RORC (0.49) | RORCWDR91 | |
| SCHEMBL28581760 | 0.86 | RORC (0.49) | RORCWDR91 | |
| SCHEMBL23636852 | 0.84 | RORC (0.52) | RORCHDAC6SMYD3 | |
| SCHEMBL23636636 | 0.84 | CYP1A2 (0.54) | RORC | |
| SCHEMBL23636782 | 0.83 | RORC (0.51) | RORC | |
| SCHEMBL28708836 | 0.82 | RORC (0.55) | RORC | |
| SCHEMBL28708837 | 0.82 | RORC (0.55) | RORC | |
| SCHEMBL28584601 | 0.82 | RORC (0.48) | RORC | |
| SCHEMBL28584604 | 0.82 | RORC (0.48) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139599-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |