Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23636838 | 0.84 | RORC (0.54) | RORCSMYD3HDAC6 | |
| SCHEMBL30065087 | 0.83 | RORC (0.54) | RORC | |
| SCHEMBL28582025 | 0.81 | RORC (0.52) | RORC | |
| SCHEMBL28582024 | 0.81 | RORC (0.52) | RORC | |
| SCHEMBL30065584 | 0.80 | RORC (0.55) | RORC | |
| SCHEMBL23636715 | 0.79 | RORC (0.53) | RORC | |
| SCHEMBL23636913 | 0.79 | RORC (0.53) | RORC | |
| SCHEMBL23636762 | 0.78 | WDR91 (0.55) | RORCALDH1A1MAPTALOX15KMT2A | |
| SCHEMBL30065086 | 0.77 | RORC (0.51) | RORCALDH1A1MAPTKMT2A | |
| SCHEMBL17695963 | 0.76 | RORC (0.58) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139599-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |