Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23637367 | 0.82 | CARM1 (0.37) | CYP3A4TAAR1CARM1PRMT6PRMT8 | |
| SCHEMBL8770815 | 0.77 | LCK (0.36) | KIF11CARM1PRMT6PRMT8 | |
| SCHEMBL1068540 | 0.73 | CYP3A4 (0.39) | CYP3A4KCNH2TAAR1 | |
| SCHEMBL5033519 | 0.73 | MEN1 (0.45) | KCNH2 | |
| SCHEMBL8773594 | 0.71 | SIGMAR1 (0.50) | CYP3A4CYP2D6KCNH2 | |
| SCHEMBL23637520 | 0.70 | — | — | |
| SCHEMBL11452258 | 0.70 | ACHE (0.52) | CYP3A4CYP2D6CYP2C9CYP2C19TAAR1 | |
| SCHEMBL18213635 | 0.69 | HTR1A (0.42) | — | |
| SCHEMBL5039661 | 0.69 | HTR1A (0.42) | — | |
| SCHEMBL29193891 | 0.69 | ACHE (0.42) | CYP3A4CYP2D6CYP2C9CYP2C19TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848378-A1 | TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME | Takasago International Corporation (JP) | 2021-07-14 | — | — | EP | disclosed |