SCHEMBL23637374

SCHEMBL23637374

CC(C)(C)OC(=O)NCCN(CCP(c1ccccc1)c1ccccc1)CCP(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CKS1B P61024 1/20 0.47
SKP1 P63208 1/20 0.47
SKP2 Q13309 1/20 0.47
IDO1 P14902 1/20 0.44
MALT1 Q9UDY8 1/20 0.42
AKT1 P31749 2/20 0.41
BCHE P06276 1/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
DRD2 P14416 3/20 0.39
SIGMAR1 Q99720 2/20 0.39
TDP1 Q9NUW8 1/20 0.38
KDM4A O75164 1/20 0.38
SYK P43405 1/20 0.38
NQO2 P16083 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637445 0.81 SIGMAR1 (0.42) CKS1BSKP1SKP2IDO1MALT1
SCHEMBL20506777 0.79 AKT1 (0.58) CKS1BSKP1SKP2IDO1MALT1
SCHEMBL12482641 0.78 TDP1 (0.56) CKS1BSKP1SKP2IDO1MALT1
SCHEMBL31165330 0.78 SYK (0.58) CKS1BSKP1SKP2IDO1AKT1
SCHEMBL23637532 0.78 GBA1 (0.41) AKT1
SCHEMBL15613432 0.78 SYK (0.58) CKS1BSKP1SKP2IDO1AKT1
SCHEMBL22771021 0.74 AKT1 (0.53) CKS1BSKP1SKP2IDO1AKT1
SCHEMBL3617075 0.74 MEN1 (0.50) CKS1BSKP1SKP2IDO1MEN1
SCHEMBL29248526 0.74 HTT (0.55) IDO1DRD2SIGMAR1TDP1SYK
SCHEMBL3628803 0.74 SYK (0.51) CKS1BSKP1SKP2IDO1AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219983-A1 TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-07-13 US disclosed
US-20230219983-A1 TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-07-13 US disclosed
US-11639362-B2 Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-05-02 US disclosed
US-11639362-B2 Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-05-02 US disclosed
EP-3848378-A1 TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME Takasago International Corporation (JP) 2021-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219983-A1 TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME ADH4, ADH5, PF4 CKS1B 3084/4885SKP1 1910/4885SKP2 3149/4885
US-11639362-B2 Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same ADH4, ADH5, PF4 CKS1B 3084/4885SKP1 1910/4885SKP2 3149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.