Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 4/20 | 0.35 |
| ▸ | SKP1 | P63208 | 4/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055428 | 0.74 | KDM4E (0.36) | CKS1BSKP1SKP2RETKDM4E | |
| SCHEMBL23055432 | 0.69 | RET (0.36) | CKS1BSKP1SKP2RETPIK3R1 | |
| SCHEMBL24784245 | 0.68 | RET (0.34) | CKS1BSKP1SKP2RETJAK3 | |
| SCHEMBL31531412 | 0.65 | PLA2G10 (0.39) | WNT1GSK3BDYRK1A | |
| SCHEMBL23055346 | 0.65 | — | — | |
| SCHEMBL21591643 | 0.60 | CKS1B (0.55) | CKS1BSKP1SKP2CRBNALDH1A1 | |
| SCHEMBL23639174 | 0.60 | CKS1B (0.39) | CKS1BSKP1SKP2KDM4EALDH1A1 | |
| SCHEMBL23055431 | 0.59 | GRIN2B (0.38) | PTPN11 | |
| SCHEMBL7346164 | 0.59 | UBE2T (0.44) | RETCRBNWNT1GSK3BDYRK1A | |
| SCHEMBL19785238 | 0.59 | RET (0.45) | CKS1BSKP1SKP2RETJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141041-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | 大日本住友製薬株式会社 | 2021-07-15 | — | — | WO | disclosed |