SCHEMBL24784245

SCHEMBL24784245

CC1(C)CCN(c2cnc(C=N)c(NCC(=O)OC(C)(C)C)n2)CC1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RET P07949 9/20 0.34
CKS1B P61024 4/20 0.34
SKP1 P63208 4/20 0.34
SKP2 Q13309 4/20 0.34
F2 P00734 1/20 0.34
F10 P00742 1/20 0.34
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34
PGK1 P00558 1/20 0.34
CCNT1 O60563 1/20 0.33
EGFR P00533 1/20 0.31
LCK P06239 1/20 0.31
JAK3 P52333 1/20 0.31
CNR1 P21554 1/20 0.31
SYK P43405 1/20 0.31
PIN1 Q13526 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23639175 0.86 CKS1B (0.40) CKS1BSKP1SKP2JAK3SYK
SCHEMBL23055432 0.83 RET (0.36) RETCKS1BSKP1SKP2F2
SCHEMBL23055616 0.77 STK17B (0.39) F2F10F7F3CCNT1
SCHEMBL23639160 0.72 MAPKAPK2 (0.36) F2F10F7F3CCNT1
SCHEMBL23055252 0.69 KMT2A (0.38) CKS1BSKP1SKP2
SCHEMBL23055428 0.69 KDM4E (0.36) RETCKS1BSKP1SKP2
SCHEMBL23639161 0.68 CKS1B (0.35) RETCKS1BSKP1SKP2JAK3
SCHEMBL23639047 0.67 KMT2A (0.42) CKS1BSKP1SKP2F2F10
SCHEMBL23639064 0.66 STK17B (0.47) F2F10F7F3CCNT1
SCHEMBL13195467 0.63 METAP1 (0.37) CCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4104861-A1 THERAPEUTIC AGENT FOR TAUOPATHIES Sumitomo Pharma Co., Ltd. (JP) 2022-12-21 EP disclosed