SCHEMBL8979455

SCHEMBL8979455

CCCCCC(CCCCC)(OC(c1ccccc1)(c1ccccc1)c1ccccc1)C(O)CO

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.36
KMT2A Q03164 6/20 0.36
ATM Q13315 1/20 0.36
KIF11 P52732 1/20 0.34
GAA P10253 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CERT1 Q9Y5P4 3/20 0.32
GRIN1 Q05586 4/20 0.32
GRIN2A Q12879 4/20 0.32
GRIN2D O15399 3/20 0.32
GRIN2C Q14957 3/20 0.32
GRIN2B Q13224 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3807431 0.79 USP2 (0.37) MEN1KMT2A
SCHEMBL11150089 0.78 USP2 (0.40) MEN1KMT2A
SCHEMBL10357997 0.78 USP2 (0.40) MEN1KMT2A
SCHEMBL8979350 0.74 ALDH1A1 (0.41) MEN1KMT2AKIF11
SCHEMBL4394710 0.73 USP2 (0.39) MEN1KMT2A
SCHEMBL2363953 0.72 MEN1 (0.41) MEN1KMT2AATMGAASIGMAR1
SCHEMBL4348576 0.72 LTA4H (0.44)
SCHEMBL8842885 0.71 LMNA (0.41) MEN1KMT2A
SCHEMBL30865104 0.70 SIGMAR1 (0.40) MEN1KMT2AGAASIGMAR1
SCHEMBL9168403 0.70 LTA4H (0.38) MEN1KMT2AATMKIF11GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710225-A1 FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES PROGEN Biotechnik GmbH (DE) 1996-05-08 EP disclosed
WO-1995032181-A1 FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES PROGEN BIOTECHNIK GMBH (DE) 1995-11-30 WO disclosed