Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23640556 | 1.00 | KDM4E (0.48) | KDM4ETSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL10526489 | 0.94 | KDM4E (0.43) | KDM4ETSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL8620807 | 0.86 | KDM4E (0.43) | KDM4ETSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL23640555 | 0.80 | KDM4E (0.48) | KDM4EMAPK1ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL16800280 | 0.75 | KDM4E (0.34) | KDM4ETSHRALDH1A1TDP1MEN1 | |
| SCHEMBL106226 | 0.73 | KDM4E (0.51) | KDM4ETSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL19832321 | 0.71 | L3MBTL1 (0.45) | KDM4EALDH1A1TDP1KMT2AHTT | |
| SCHEMBL10525607 | 0.71 | ALDH1A1 (0.43) | KDM4ETSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL10523659 | 0.71 | ALDH1A1 (0.43) | KDM4ETSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL11535450 | 0.70 | PTGIR (0.46) | KDM4ETSHRALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133594-A1 | METHODS FOR HYDROAMINOALKYLATION OF OLEFINS AND GROUP 4 METAL COMPLEXES USEFUL IN SUCH METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-06-30 | — | — | WO | disclosed |