Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23640556 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL24575404 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL16800285 | 0.75 | CTSS (0.34) | KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL10526489 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL23640555 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL5377178 | 0.64 | KDM4E (0.47) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL8620807 | 0.64 | KDM4E (0.43) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL11713670 | 0.62 | — | — | |
| SCHEMBL539073 | 0.62 | — | — | |
| SCHEMBL19832320 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056141-B2 | Thiol-ene click chemistry for drug conjugates | SYNCHEM, INC. (US) | 2015-06-16 | — | — | US | disclosed |
| US-9056141-B2 | Thiol-ene click chemistry for drug conjugates | SYNCHEM, INC. (US) | 2015-06-16 | — | — | US | disclosed |