SCHEMBL23640901

SCHEMBL23640901

CCC(C)Cc1c(C)oc2ccc(N)cc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
MAPT P10636 4/20 0.40
GFER P55789 1/20 0.40
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 3/20 0.39
HPGD P15428 3/20 0.39
MEN1 O00255 2/20 0.39
MAPK1 P28482 2/20 0.36
SRC P12931 2/20 0.35
EGFR P00533 1/20 0.34
CDK9 P50750 1/20 0.33
DYRK1A Q13627 1/20 0.33
DYRK2 Q92630 1/20 0.33
CA9 Q16790 2/20 0.33
GAA P10253 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8547804 0.72 NPC1 (0.41) NPC1RAB9ASMN1; SMN2MAPTGFER
Hydrochloric Acid SCHEMBL8553027 0.71 NPC1 (0.40) NPC1RAB9ASMN1; SMN2MAPTGFER
SCHEMBL14161827 0.70 ALDH1A1 (0.46) NPC1RAB9ASMN1; SMN2MAPTGFER
SCHEMBL8229629 0.70 CDK9 (0.59) NPC1RAB9ASMN1; SMN2MAPTGFER
SCHEMBL28428780 0.68 MAPT (0.47) NPC1RAB9ASMN1; SMN2MAPTGFER
SCHEMBL21782796 0.67 SMN1; SMN2 (0.42) NPC1RAB9ASMN1; SMN2MAPTGFER
SCHEMBL17456346 0.65 NPC1 (0.47) NPC1RAB9ASMN1; SMN2MAPTGFER
SCHEMBL20226503 0.65 ADRA2B (0.41) MAPTKDM4EALDH1A1MAPK1GAA
SCHEMBL11228880 0.65 SMN1; SMN2 (0.67) NPC1RAB9ASMN1; SMN2MAPTGFER
SCHEMBL30340803 0.65 NPC1 (0.78) NPC1RAB9ASMN1; SMN2MAPTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3663308-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2021-07-14 EP disclosed