Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223775 | 0.86 | ALDH1A1 (0.57) | SMN1; SMN2NPC1RAB9AMAPTGFER | |
| SCHEMBL8229629 | 0.85 | CDK9 (0.59) | SMN1; SMN2NPC1RAB9AMAPTGFER | |
| SCHEMBL4381356 | 0.81 | RAB9A (1.00) | SMN1; SMN2NPC1RAB9AMAPTGFER | |
| SCHEMBL30901818 | 0.79 | KMT2A (0.60) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL11618318 | 0.74 | RAB9A (0.85) | SMN1; SMN2NPC1RAB9AMAPTGFER | |
| SCHEMBL11233028 | 0.73 | KDM1A (0.53) | MAPTKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL9334571 | 0.73 | LMNA (0.43) | SMN1; SMN2NPC1RAB9AMAPTGFER | |
| SCHEMBL9499154 | 0.73 | AKR1B1 (0.43) | SMN1; SMN2RAB9AMAPTKMT2AMAPK1 | |
| SCHEMBL9333747 | 0.73 | ALDH2 (0.41) | SMN1; SMN2NPC1RAB9AMAPTGFER | |
| SCHEMBL9333604 | 0.73 | ALDH2 (0.40) | SMN1; SMN2NPC1RAB9AMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309353-A | ANTI-ALLERGIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4205082-A | ANTI-ALLERGIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |