SCHEMBL2364296

SCHEMBL2364296

C=CCOc1ccc(C(=O)Oc2ccc(C#N)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
ALDH1A1 P00352 2/20 0.49
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
HIF1A Q16665 1/20 0.47
POLB P06746 2/20 0.47
ADRB2 P07550 1/20 0.45
ADRB1 P08588 1/20 0.45
ADRB3 P13945 1/20 0.45
RAB9A P51151 3/20 0.45
NPC1 O15118 3/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
F2 P00734 1/20 0.45
PARP15 Q460N3 1/20 0.44
PARP10 Q53GL7 1/20 0.44
PARP2 Q9UGN5 1/20 0.44
CHRNB2 P17787 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA4 P43681 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2831629 1.00 MAPT (0.49) MAPTALDH1A1CYP1A2CYP2D6HIF1A
SCHEMBL10581417 0.96 MMP2 (0.48) MAPTALDH1A1CYP1A2CYP2D6HIF1A
SCHEMBL5855876 0.96 MMP2 (0.48) MAPTALDH1A1CYP1A2CYP2D6HIF1A
SCHEMBL6394837 0.94 ALDH1A1 (0.51) MAPTALDH1A1CYP1A2CYP2D6HIF1A
SCHEMBL8026374 0.89 NPC1 (0.52) MAPTALDH1A1POLBADRB2ADRB1
SCHEMBL7619158 0.89 NPC1 (0.52) MAPTALDH1A1POLBADRB2ADRB1
SCHEMBL5088891 0.88 MAPT (0.43) MAPTALDH1A1POLBADRB2ADRB1
SCHEMBL19460818 0.86 ALDH1A1 (0.54) MAPTALDH1A1CYP1A2CYP2D6HIF1A
SCHEMBL9650787 0.86 POLB (0.46) MAPTALDH1A1CYP1A2CYP2D6HIF1A
SCHEMBL18763586 0.85 ALDH1A1 (0.59) MAPTALDH1A1CYP1A2CYP2D6HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853577-A Method for preparing dimethyl ether and co-producing p-hydroxybenzonitrile 三门峡环宇生化科技有限公司 2022-08-05 CN disclosed
CN-111718487-B Preparation method of click-modified polysiloxane side chain liquid crystal polymer 苏州美嘉写智能显示科技有限公司 2022-01-28 CN disclosed
CN-111718487-A Preparation method of click-modified polysiloxane side chain liquid crystal polymer 苏州美嘉写智能显示科技有限公司 2020-09-29 CN disclosed
US-9638848-B2 Patterned phase difference film and method for manufacturing same DAI NIPPON PRINTING CO., LTD. (JP) 2017-05-02 US disclosed
US-20150168617-A1 INFRARED-RAY REFLECTIVE MEMBER DAINIPPON PRINTING CO LTD (JP) 2015-06-18 US disclosed
US-20140268002-A1 PATTERNED PHASE DIFFERENCE FILM AND METHOD FOR MANUFACTURING SAME DAI NIPPON PRINTING CO., LTD. (JP) 2014-09-18 US disclosed
EP-1355971-B1 PHOTOSENSITIVE POLYIMIDES FOR OPTICAL ALIGNMENT OF LIQUID CRYSTALS ELSICON INC (US) 2014-06-25 EP disclosed
US-8362151-B2 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. (US) 2013-01-29 US disclosed
US-8355203-B2 Optical functional film, retardation film, composition for forming optical functional layer and producing method of optical functional film DAI NIPPON PRINTING CO., LTD. (JP) 2013-01-15 US disclosed
EP-2513157-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS Li, Chunhong (US) 2012-10-24 EP disclosed
EP-0460504-B1 Dichroic azo dyes HERCULES INC (US) 1994-04-27 EP disclosed
US-5211877-A Crosslinked resins CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1993-05-18 US disclosed
US-5097029-A Hydrolysis, alkylation, intermediates for azo dyes HERCULES INCORPORATED (US) 1992-03-17 US disclosed
EP-0471277-A2 Silanol compounds, polymerizable monomers and polymers having mesogenic groups SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-02-19 EP disclosed
EP-0460504-A1 Dichroic azo dyes HERCULES INCORPORATED (US) 1991-12-11 EP disclosed
US-5032009-A Polarized light exposure HERCULES INCORPORATED (US) 1991-07-16 US disclosed
EP-0432735-A2 Liquid crystal coupled dichroic dyes HERCULES INCORPORATED (US) 1991-06-19 EP disclosed
EP-0406812-A2 Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine HERCULES INCORPORATED (US) 1991-01-09 EP disclosed
US-4974941-A Process of aligning and realigning liquid crystal media HERCULES INCORPORATED (US) 1990-12-04 US disclosed
EP-0387059-A2 Process of aligning liquid crystal media HERCULES INCORPORATED (US) 1990-09-12 EP disclosed