Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650616 | 0.88 | POLB (0.44) | POLBTP53MAPTLMNAMMP2 | |
| SCHEMBL5855876 | 0.88 | MMP2 (0.48) | POLBTP53MAPTLMNAADORA3 | |
| SCHEMBL10581417 | 0.88 | MMP2 (0.48) | POLBTP53MAPTLMNAADORA3 | |
| SCHEMBL2831629 | 0.86 | MAPT (0.49) | POLBMAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL2364296 | 0.86 | MAPT (0.49) | POLBMAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL10582715 | 0.84 | MAPT (0.43) | POLBTP53MAPTLMNATHRB | |
| SCHEMBL10452305 | 0.83 | MMP2 (0.41) | TP53MAPTADORA3ADORA1MMP2 | |
| SCHEMBL10451577 | 0.83 | ALDH1A1 (0.39) | MAPTADORA3ADORA1MMP2MMP3 | |
| SCHEMBL12242462 | 0.82 | POLB (0.41) | POLBTP53MAPTLMNAMMP2 | |
| SCHEMBL6394837 | 0.81 | ALDH1A1 (0.51) | POLBMAPTALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112523-A | High clearing point for liquid crystal displays | CHISSO CORPORATION (JP) | 1992-05-12 | — | — | US | claimed |