Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13929725 | 0.90 | ACHE (0.55) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL13929729 | 0.88 | ACHE (0.61) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL5653057 | 0.87 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL23643207 | 0.87 | CSF1R (0.55) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL19243095 | 0.85 | KMT2A (0.53) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL11089861 | 0.82 | GAA (0.58) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL17997429 | 0.82 | MRGPRX4 (0.59) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL9615213 | 0.81 | ALDH1A1 (0.69) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL23643012 | 0.81 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8171761 | 0.80 | CALM1 (0.65) | SMN1; SMN2MAPTALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848368-A1 | TROPOMYOSIN-RELATED KINASE (TRK) INHIBITORS | Genzyme Corporation (US) | 2021-07-14 | — | — | EP | disclosed |