SCHEMBL236430

SCHEMBL236430

O=C(O)[CH]N1C(=O)CCC1=O

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 1/20 0.31
FGF2 P09038 1/20 0.30
ITGB3 P05106 1/20 0.30
ITGB1 P05556 1/20 0.30
ITGAV P06756 1/20 0.30
ITGA4 P13612 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1314060 0.75 BLM (0.38) CA12CA1CA9RAB9ASMN1; SMN2
SCHEMBL1442376 0.69 TSHR (0.36) CA12CA1CA9RAB9ASMN1; SMN2
SCHEMBL20425084 0.67 AKR1C3 (0.33) CA12CA1CA9
SCHEMBL820023 0.65
Acrylic Acid SCHEMBL34299 0.65 LMNA (0.48) CA12CA1CA9
Acrylic Acid SCHEMBL31065455 0.64 LMNA (0.40) RAB9ASMN1; SMN2FGF2
SCHEMBL25432412 0.63 BRD4 (0.33)
SCHEMBL236431 0.63 TSHR (0.56) CA12CA9RAB9ASMN1; SMN2TSHR
Bicarbonate SCHEMBL6150295 0.63 CA1 (0.38) CA12CA1CA9RAB9ASMN1; SMN2
Bicarbonate SCHEMBL14917 0.63 CA1 (0.38) CA12CA1CA9RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 778 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023129438-A1 HYDROGEL COMPOSITIONS FOR USE FOR DEPLETION OF TUMOR ASSOCIATED MACROPHAGES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-07-06 WO claimed
CN-109810198-B Site-specific GLP-2 conjugates utilizing immunoglobulin fragments 韩美科学株式会社 2023-06-06 CN claimed
US-20230090790-A1 LONG-ACTING CONJUGATES OF GLP-2 DERIVATIVES HANMI PHARM. CO., LTD. (KR) 2023-03-23 US claimed
CN-108136276-B Protein complexes linked by using specific sites of immunoglobulin fragments 韩美药品株式会社 2023-02-28 CN claimed
US-11571493-B2 Co-precipitation method NEOMEND, INC. (US) 2023-02-07 US claimed
US-20230027238-A1 METHODS OF TREATMENT USING G-CSF PROTEIN COMPLEX SPECTRUM PHARMACEUTICALS, INC. (US) 2023-01-26 US claimed
US-11389508-B2 Protein complex by use of a specific site of an immunoglobulin fragment for linkage HANMI PHARM. CO., LTD. (KR) 2022-07-19 US claimed
CN-114364393-A Methods of treatment using G-CSF protein complexes 光谱制药有限公司 2022-04-15 CN claimed
WO-2021261712-A1 HEMOGLOBIN DERIVATIVE CO-CONJUGATED WITH FATTY ACID-LINKED PEG AND ALKOXY PEG AS A BLOOD SUBSTITUTE SUNBIO, INC. (KR) 2021-12-30 WO claimed
US-20210401949-A1 Hemoglobin Derivative Co-conjugated with Fatty Acid-linked PEG and Alkoxy PEG as a Blood Substitute SUNBIO, INC. (KR) 2021-12-30 US claimed
EP-1601698-A4 PHYSIOLOGICALLY ACTIVE POLYPEPTIDE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE HANMI PHARM IND CO LTD (KR) 2006-05-03 EP claimed
CN-1761684-A Physiologically active polypeptide conjugates with extended in vivo half-life HANMI PHARM IND CO LTD (KR) 2006-04-19 CN claimed
CN-1723219-A Protein complex using immunoglobulin fragment and method for preparing the same HANMI PHARM IND CO LTD (KR) 2006-01-18 CN claimed
EP-1613644-A1 PEG-PHYSIOLOGICALLY ACTIVE POLYPEPTIDE HOMODIMER COMPLEX HAVING PROLONGED IN VIVO HALF-LIFE AND PROCESS FOR THE PREPARATION THEREOF Hanmi Pharm. Co., Ltd. (KR) 2006-01-11 EP claimed
EP-1601698-A1 PHYSIOLOGICALLY ACTIVE POLYPEPTIDE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE Hanmi Pharm. Co., Ltd. (KR) 2005-12-07 EP claimed
US-20050176108-A1 Physiologically active polypeptide conjugate having prolonged in vivo half-life HANMI PHARM. CO., LTD. (KR) 2005-08-11 US claimed
WO-2005047336-A1 PROTEIN COMPLEX USING IMMUNOGLOBULIN FRAGMENT ANDMETHOD FOR THE PREPARATION THEREOF HANMI PHARMACEUTICAL. CO. LTD. (KR) 2005-05-26 WO claimed
WO-2004087739-A1 PEG-PHYSIOLOGICALLY ACTIVE POLYPEPTIDE HOMODIMER COMPLEX HAVING PROLONGED IN VIVO HALF-LIFE AND PROCESS FOR THE PREPARATION THEREOF HANMI PHARM. CO. LTD. (KR) 2004-10-14 WO claimed
WO-2004081053-A1 PHYSIOLOGICALLY ACTIVE POLYPEPTIDE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE HANMI PHARM. CO. LTD. (KR) 2004-09-23 WO claimed
US-20040180054-A1 Physiologically active polypeptide conjugate having prolonged in vivo half-life HANMI PHARM. CO., LTD. 2004-09-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230090790-A1 LONG-ACTING CONJUGATES OF GLP-2 DERIVATIVES GIPR, VIP, GLP1R CA12 1697/4885CA1 2335/4885CA9 2268/4885
US-20210401949-A1 Hemoglobin Derivative Co-conjugated with Fatty Acid-linked PEG and Alkoxy PEG as a Blood Substitute HBG2, HBB, HBG1 CA12 845/4885CA1 2849/4885CA9 614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.