Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23643398 | 0.77 | GAA (0.47) | MAPTGAANPC1RAB9ACA1 | |
| SCHEMBL23643400 | 0.74 | TTR (0.38) | MAPTGAANPC1RAB9AAURKA | |
| SCHEMBL11613891 | 0.73 | ALDH1A1 (0.45) | MAPTGAACA1CA2LMNA | |
| SCHEMBL13955883 | 0.71 | IGF1R (0.59) | BRAFPTK2AURKAKDRAURKB | |
| SCHEMBL8629439 | 0.70 | MAPT (0.64) | MAPTGAANPC1RAB9APKM | |
| SCHEMBL8734640 | 0.68 | PKM (0.48) | TUBB1MAPTGAACA12CA1 | |
| SCHEMBL23643492 | 0.67 | MAPT (0.42) | MAPTKDRIGF1RKMT2AMEN1 | |
| SCHEMBL6577706 | 0.66 | PKM (0.47) | TUBB1MAPTGAACA12CA1 | |
| SCHEMBL3269159 | 0.66 | ABCG2 (0.67) | ABCG2MAPTGAANPC1RAB9A | |
| SCHEMBL17394819 | 0.66 | POLB (0.56) | MAPTGAAPTK2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141984-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2021-07-15 | — | — | WO | disclosed |