Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28432146 | 0.79 | MEN1 (0.44) | GAAMEN1KMT2AL3MBTL1G6PD | |
| SCHEMBL23643419 | 0.78 | NFKB1 (0.53) | GAAMEN1KMT2AL3MBTL1G6PD | |
| SCHEMBL23643400 | 0.78 | TTR (0.38) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11613891 | 0.77 | ALDH1A1 (0.45) | GAAMEN1KMT2ACA1CA2 | |
| SCHEMBL23643401 | 0.77 | TUBB4A (0.43) | GAAMEN1KMT2ACA1CA2 | |
| SCHEMBL18639447 | 0.75 | GAA (0.74) | GAAMEN1KMT2AL3MBTL1G6PD | |
| SCHEMBL9123851 | 0.74 | KMT2A (0.43) | GAAMEN1KMT2AL3MBTL1G6PD | |
| SCHEMBL15488091 | 0.71 | MEN1 (0.41) | GAAMEN1KMT2AL3MBTL1G6PD | |
| SCHEMBL11615704 | 0.71 | RAB9A (0.49) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23643492 | 0.71 | MAPT (0.42) | MEN1KMT2AALOX5MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087837-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | Musc Foundation for Research Development (US) | 2022-11-16 | — | — | EP | claimed |
| EP-4087837-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | Musc Foundation for Research Development (US) | 2022-11-16 | — | — | EP | disclosed |
| WO-2021141984-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2021-07-15 | — | — | WO | disclosed |