Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | GSK3A | P49840 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | STK10 | O94804 | 1/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961759 | 0.86 | TTR (0.44) | TTRHSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL23643511 | 0.81 | NFKB1 (0.52) | TTRHSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL23643492 | 0.79 | MAPT (0.42) | ALDH1A1MAPTCYP1A2NFKB1MEN1 | |
| SCHEMBL23643398 | 0.78 | GAA (0.47) | ALDH1A1MAPTGAANPC1RAB9A | |
| SCHEMBL11613891 | 0.74 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TSHRMAPTGAA | |
| SCHEMBL23643401 | 0.74 | TUBB4A (0.43) | MAPTGAANPC1RAB9ACYP1A2 | |
| SCHEMBL8629687 | 0.71 | POLB (0.50) | ALDH1A1MAPTGAANPC1RAB9A | |
| SCHEMBL11616820 | 0.69 | SYK (0.55) | CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL655459 | 0.67 | AURKA (0.61) | GSK3BGSK3ASLKAURKAMAPK8 | |
| SCHEMBL17612171 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087837-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | Musc Foundation for Research Development (US) | 2022-11-16 | — | — | EP | claimed |
| EP-4087837-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | Musc Foundation for Research Development (US) | 2022-11-16 | — | — | EP | disclosed |
| WO-2021141984-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2021-07-15 | — | — | WO | disclosed |