Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TXN | P10599 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537458 | 0.86 | CYP1A2 (0.45) | NFKB1MEN1KMT2AGAAG6PD | |
| SCHEMBL11537650 | 0.82 | CYP1A2 (0.45) | NFKB1MEN1KMT2AGAAMAPT | |
| SCHEMBL23643511 | 0.81 | NFKB1 (0.52) | NFKB1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL14268288 | 0.81 | NFKB1 (0.57) | NFKB1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL9123851 | 0.81 | KMT2A (0.43) | MEN1KMT2AGAAG6PDL3MBTL1 | |
| SCHEMBL17018621 | 0.79 | NFKB1 (0.68) | NFKB1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL8973147 | 0.78 | NFKB1 (0.62) | NFKB1MEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL23643398 | 0.78 | GAA (0.47) | MEN1KMT2AGAAG6PDL3MBTL1 | |
| SCHEMBL10870243 | 0.77 | NFKB1 (0.45) | NFKB1MEN1KMT2AGAAMAPT | |
| SCHEMBL28432146 | 0.75 | MEN1 (0.44) | NFKB1MEN1KMT2AGAAG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141984-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2021-07-15 | — | — | WO | disclosed |